HTLV1 Target gene Detail Information

> RAPGEF1 Gene Search Result


Gene Information
Gene Name RAPGEF1
Gene ID 2889
Gene Full Name Rap guanine nucleotide exchange factor 1
Gene Alias C3G|GRF2
Transcripts ENSG00000107263
Virus HTLV1
Gene Type protein-coding
HPA Location Info Vesicles;
Membrane Info Plasma proteins, Predicted intracellular proteins
Uniport_ID Q13905
HGNC ID HGNC:4568
OMIM ID 600303
Summary This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
Target gene [RAPGEF1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6001234 chr9 240 140 142 522 View
6006743 chr9 62 2 0 64 View
6011630 chr9 21 3 2 26 View

Target gene [RAPGEF1] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - RAPGEF1 peak across samples

Peak Plot