HTLV1 Target gene Detail Information

> RAPGEF4 Gene Search Result


Gene Information
Gene Name RAPGEF4
Gene ID 11069
Gene Full Name Rap guanine nucleotide exchange factor 4
Gene Alias CAMP-GEFII|CGEF2|EPAC|EPAC 2|EPAC2|Nbla00496
Transcripts ENSG00000091428
Virus HTLV1
Gene Type protein-coding
HPA Location Info Focal adhesion sites;Plasma membrane, Basal body, Cytosol, Mid piece;
Membrane Info Predicted intracellular proteins
Uniport_ID Q8WZA2
HGNC ID HGNC:16626
OMIM ID 606058
Summary Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in Ras protein signal transduction; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane; and regulation of postsynapse organization. Predicted to act upstream of or within with a positive effect on hormone secretion. Predicted to act upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway; regulation of exocytosis; and secretion by cell. Predicted to be located in membrane. Predicted to be active in several cellular components, including glutamatergic synapse; hippocampal mossy fiber to CA3 synapse; and postsynaptic density. Implicated in autistic disorder. [provided by Alliance of Genome Resources, Apr 2025]
Target gene [RAPGEF4] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6007186 chr2 23 32 3 58 View

Target gene [RAPGEF4] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - RAPGEF4 peak across samples

Peak Plot