Gene Information
|
Gene Name
|
RASD1 |
|
Gene ID
|
51655
|
|
Gene Full Name
|
ras related dexamethasone induced 1 |
|
Gene Alias
|
AGS1|DEXRAS1|MGC:26290 |
|
Transcripts
|
ENSG00000108551
|
|
Virus
|
VZV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm;Plasma membrane;
|
|
Membrane Info
|
Human disease related genes, Predicted intracellular proteins |
|
Uniport_ID
|
Q9Y272
|
|
HGNC ID
|
HGNC:15828
|
|
OMIM ID
|
605550 |
|
Summary
|
This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2011] |
Target gene [RASD1] related to virus gene/protein/region
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
Target gene [RASD1] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE121385
|
RNA-seq |
6 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE120375
|
RNA-seq |
24 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE175797
|
RNA-seq |
6 |
Illumina NextSeq 500 (Homo sapiens) |
|
|