VZV Target gene Detail Information

> RASD1 Gene Search Result


Gene Information
Gene Name RASD1
Gene ID 51655
Gene Full Name ras related dexamethasone induced 1
Gene Alias AGS1|DEXRAS1|MGC:26290
Transcripts ENSG00000108551
Virus VZV
Gene Type protein-coding
HPA Location Info Nucleoplasm;Plasma membrane;
Membrane Info Human disease related genes, Predicted intracellular proteins
Uniport_ID Q9Y272
HGNC ID HGNC:15828
OMIM ID 605550
Summary This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2011]
Target gene [RASD1] related to virus gene/protein/region

Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section


ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 27795423 Y881F
gB
ORF31
Cell line
R
T
View
2 27795423 Y920F
gB
ORF31
Cell line
R
T
View

Target gene [RASD1] related to Omics data
Data ID Experiment type Sample number Platform
GSE121385 RNA-seq 6 Illumina HiSeq 2500 (Homo sapiens)
GSE120375 RNA-seq 24 Illumina HiSeq 2500 (Homo sapiens)
GSE175797 RNA-seq 6 Illumina NextSeq 500 (Homo sapiens)