HTLV1 Target gene Detail Information

> RBPJ Gene Search Result


Gene Information
Gene Name RBPJ
Gene ID 3516
Gene Full Name recombination signal binding protein for immunoglobulin kappa J region
Gene Alias AOS3|CBF-1|CBF1|IGKJRB|IGKJRB1|KBF2|RBP-J|RBP-J kappa|RBP-JK|RBPJK|RBPSUH|SUH|csl
Transcripts ENSG00000168214
Virus HTLV1
Gene Type protein-coding
HPA Location Info Nucleoplasm;
Membrane Info Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID Q06330
HGNC ID HGNC:5724
OMIM ID 147183
Summary The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. [provided by RefSeq, Oct 2013]
Target gene [RBPJ] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6007295 chr4 57 0 0 57 View
6007536 chr4 8 40 6 54 View
6012779 chr4 21 0 0 21 View
6015471 chr4 0 1 13 14 View
6018024 chr4 2 8 0 10 View
6021657 chr4 5 0 0 5 View
6024509 chr4 2 1 0 3 View
6026187 chr4 0 2 0 2 View

Target gene [RBPJ] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732
Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - RBPJ peak across samples

Peak Plot