Gene Information
|
Gene Name
|
RGS6 |
|
Gene ID
|
9628
|
|
Gene Full Name
|
regulator of G protein signaling 6 |
|
Gene Alias
|
GAP|HA117|S914 |
|
Transcripts
|
ENSG00000182732
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm;Nucleoli, Vesicles; 
|
|
Membrane Info
|
Predicted intracellular proteins |
|
Uniport_ID
|
P49758
|
|
HGNC ID
|
HGNC:10002
|
|
OMIM ID
|
603894 |
|
Summary
|
This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.[provided by RefSeq, Mar 2011] |
Target gene [RGS6] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6005409 |
chr14 |
86 |
1 |
1 |
88 |
View |
| 6008371 |
chr14 |
28 |
17 |
1 |
46 |
View |
| 6008642 |
chr14 |
29 |
4 |
10 |
43 |
View |
| 6019154 |
chr14 |
7 |
1 |
0 |
8 |
View |
| 6021002 |
chr14 |
6 |
0 |
0 |
6 |
View |
| 6023565 |
chr14 |
3 |
1 |
0 |
4 |
View |
| 6027218 |
chr14 |
0 |
2 |
0 |
2 |
View |
Target gene [RGS6] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - RGS6 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
