HTLV1 Target gene Detail Information

> RORA Gene Search Result


Gene Information
Gene Name RORA
Gene ID 6095
Gene Full Name RAR related orphan receptor A
Gene Alias IDDECA|NR1F1|ROR1|ROR2|ROR3|RORa1|RORalpha|RZR-ALPHA|RZRA
Transcripts ENSG00000069667
Virus HTLV1
Gene Type protein-coding
HPA Location Info Nucleoli;
Membrane Info Disease related genes, Human disease related genes, Metabolic proteins, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors
Uniport_ID P35398
HGNC ID HGNC:10258
OMIM ID 600825
Summary The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2014]
Target gene [RORA] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6002715 chr15 49 29 137 215 View
6004959 chr15 85 15 0 100 View
6004960 chr15 85 15 0 100 View
6004961 chr15 85 15 0 100 View
6008034 chr15 41 8 0 49 View
6008496 chr15 38 6 0 44 View
6012626 chr15 8 14 0 22 View
6019120 chr15 8 0 0 8 View
6022063 chr15 3 1 1 5 View
6023016 chr15 3 1 0 4 View
6025497 chr15 0 3 0 3 View
6025951 chr15 1 0 1 2 View
6026285 chr15 2 0 0 2 View
6028762 chr15 1 0 0 1 View
6031733 chr15 0 0 0 0 View

Target gene [RORA] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - RORA peak across samples

Peak Plot