Gene Information
|
Gene Name
|
ROS1 |
|
Gene ID
|
6098
|
|
Gene Full Name
|
ROS proto-oncogene 1, receptor tyrosine kinase |
|
Gene Alias
|
MCF3|ROS|c-ros-1 |
|
Transcripts
|
ENSG00000047936
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Vesicles; 
|
|
Membrane Info
|
Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins |
|
Uniport_ID
|
P08922
|
|
HGNC ID
|
HGNC:10261
|
|
OMIM ID
|
165020 |
|
Summary
|
This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. [provided by RefSeq, Jul 2008] |
Target gene [ROS1] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6001604 |
chr6 |
26 |
341 |
20 |
387 |
View |
| 6001715 |
chr6 |
46 |
194 |
121 |
361 |
View |
| 6029955 |
chr6 |
1 |
0 |
0 |
1 |
View |
| 6030462 |
chr6 |
0 |
0 |
0 |
0 |
View |
| 6030606 |
chr6 |
0 |
0 |
0 |
0 |
View |
| 6033477 |
chr6 |
0 |
0 |
0 |
0 |
View |
Target gene [ROS1] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - ROS1 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
