HTLV1 Target gene Detail Information

> RPTOR Gene Search Result


Gene Information
Gene Name RPTOR
Gene ID 57521
Gene Full Name regulatory associated protein of MTOR complex 1
Gene Alias KOG1|Mip1
Transcripts ENSG00000141564
Virus HTLV1
Gene Type protein-coding
HPA Location Info Vesicles, Lysosomes;Cytosol;
Membrane Info Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q8N122
HGNC ID HGNC:30287
OMIM ID 607130
Summary This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Target gene [RPTOR] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6000036 chr17 4419 2098 863 7380 View
6001455 chr17 262 119 50 431 View
6002675 chr17 155 13 51 219 View
6006298 chr17 59 12 0 71 View
6006837 chr17 1 60 2 63 View
6009183 chr17 18 2 19 39 View
6010407 chr17 27 4 0 31 View
6019480 chr17 7 1 0 8 View
6026338 chr17 2 0 0 2 View

Target gene [RPTOR] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - RPTOR peak across samples

Peak Plot