HPV Target gene Detail Information

> RUBCN Gene Search Result


Gene Information
Gene Name RUBCN
Gene ID 9711
Gene Full Name rubicon autophagy regulator
Gene Alias KIAA0226|RUBICON|SCAR15
Transcripts ENSG00000145016
Virus HPV
Gene Type protein-coding
HPA Location Info Vesicles, Cytosol;Nucleoplasm;
Membrane Info Disease related genes, Human disease related genes, Predicted intracellular proteins
Uniport_ID Q92622
HGNC ID HGNC:28991
OMIM ID 613516
Summary The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Target gene [RUBCN] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5015899 chr3 36 0 0 36 View

Target gene [RUBCN] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE183048 		Chip-seq 24 Illumina HiSeq 4000 (Homo sapiens)
S
  GSE226620 		scRNA-seq 30 HiSeq X Ten (Homo sapiens)
S
  GSE139324 		scRNA-seq 63 Illumina NextSeq 500 (Homo sapiens)
GSE65858 Expression array 270 Illumina HumanHT-12 V4.0 expression beadchip
GSE181805 Expression array 25 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
S
  GSE164690 		scRNA-seq 51 Illumina NextSeq 500 (Homo sapiens)
GSE138080 Expression array 35 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
GSE140662 Expression array 8 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
C
  GSE143026 		ATAC-seq;Chip-seq;RNA-seq 30 Illumina HiSeq 2500 (Homo sapiens)
TCGA_CESC DNA methylation sequencing;RNA-seq 288 TCGA
GSE51993 Expression array 48 Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip


When the query gene is differentially changed in the dataset, a feature/violin plot will be displayed.


> Dataset: GSE226620 - Gene expression in cell subsets

> Dataset: GSE139324 - Gene expression in cell subsets

> Dataset: GSE164690 - Gene expression in cell subsets