HTLV1 Target gene Detail Information

> SCN4B Gene Search Result


Gene Information
Gene Name SCN4B
Gene ID 6330
Gene Full Name sodium voltage-gated channel beta subunit 4
Gene Alias ATFB17|LQT10|Navbeta4
Transcripts ENSG00000177098
Virus HTLV1
Gene Type protein-coding
HPA Location Info
Membrane Info Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters
Uniport_ID Q8IWT1
HGNC ID HGNC:10592
OMIM ID 608256
Summary The protein encoded by this gene is one of several sodium channel beta subunits. These subunits interact with voltage-gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10). Three protein-coding and one non-coding transcript variant have been found for this gene.[provided by RefSeq, Mar 2009]
Target gene [SCN4B] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6002971 chr11 73 109 12 194 View

Target gene [SCN4B] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE94732
Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - SCN4B peak across samples

Peak Plot