HTLV1 Target gene Detail Information

> SEMA3C Gene Search Result


Gene Information
Gene Name SEMA3C
Gene ID 10512
Gene Full Name semaphorin 3C
Gene Alias SEMAE|SemE
Transcripts ENSG00000075223
Virus HTLV1
Gene Type protein-coding
HPA Location Info Golgi apparatus, Cytosol;Plasma membrane;Secreted in other tissues;
Membrane Info Predicted secreted proteins
Uniport_ID Q99985
HGNC ID HGNC:10725
OMIM ID 602645
Summary This gene encodes a secreted glycoprotein that belongs to the semaphorin class 3 family of neuronal guidance cues. The encoded protein contains an N-terminal sema domain, integrin and immunoglobulin-like domains, and a C-terminal basic domain. Homodimerization and proteolytic cleavage of the C-terminal propeptide are necessary for the function of the encoded protein. It binds a neuropilin co-receptor before forming a heterotrimeric complex with an associated plexin. An increase in the expression of this gene correlates with an increase in cancer cell invasion and adhesion. Naturally occurring mutations in this gene are associated with Hirschsprung disease. [provided by RefSeq, May 2017]
Target gene [SEMA3C] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6006697 chr7 14 43 7 64 View
6015031 chr7 7 7 1 15 View
6016822 chr7 3 8 0 11 View
6020143 chr7 5 0 2 7 View
6031344 chr7 0 0 0 0 View

Target gene [SEMA3C] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - SEMA3C peak across samples

Peak Plot