Gene Information
|
Gene Name
|
SEMA6D |
|
Gene ID
|
80031
|
|
Gene Full Name
|
semaphorin 6D |
|
Gene Alias
|
- |
|
Transcripts
|
ENSG00000137872
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Plasma membrane;Golgi apparatus;Intracellular and membrane; 
|
|
Membrane Info
|
Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins |
|
Uniport_ID
|
Q8NFY4
|
|
HGNC ID
|
HGNC:16770
|
|
OMIM ID
|
609295 |
|
Summary
|
Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Several transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner. [provided by RefSeq, Nov 2010] |
Target gene [SEMA6D] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6007239 |
chr15 |
11 |
20 |
27 |
58 |
View |
| 6013164 |
chr15 |
4 |
2 |
14 |
20 |
View |
| 6020185 |
chr15 |
7 |
0 |
0 |
7 |
View |
| 6025496 |
chr15 |
2 |
1 |
0 |
3 |
View |
| 6032596 |
chr15 |
0 |
0 |
0 |
0 |
View |
Target gene [SEMA6D] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - SEMA6D peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
