Gene Name	SENP5
Gene ID	205564
Gene Full Name	SUMO specific peptidase 5
Gene Alias	-
Transcripts	ENSG00000119231
Virus	HBV
Gene Type	protein-coding
HPA Location Info
Membrane Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q96HI0
HGNC ID	HGNC:28407
OMIM ID	612845
Summary	The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001839	chr3	301	155	3	459	View
1001918	chr3	263	153	3	419	View
1001991	chr3	235	145	3	383	View
1002028	chr3	223	144	2	369	View
1002046	chr3	219	143	0	362	View
1002099	chr3	278	64	3	345	View
1002110	chr3	278	60	3	341	View
1002115	chr3	203	135	0	338	View
1002177	chr3	270	48	3	321	View
1002656	chr3	153	74	0	227	View
1008775	chr3	12	7	0	19	View
1020254	chr3	217	143	0	360	View
1020266	chr3	221	143	1	365	View
1020270	chr3	141	46	0	187	View
1021202	chr3	219	143	0	362	View
1021519	chr3	153	74	0	227	View
1021822	chr3	278	64	3	345	View
1023858	chr3	203	135	0	338	View

Data ID	Experiment type	Sample number	Platform
GSE236281	RNA-seq	12	Illumina MiSeq (Homo sapiens)
C   GSE35465	Chip-seq;RNA-seq	6	Illumina HiSeq 2000 (Homo sapiens)
C   GSE68402	Chip-seq	26	Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
GSE247322	scRNA-seq	27	Illumina NovaSeq 6000 (Homo sapiens)
TCGA_LIHC_HBV	DNA methylation sequencing;RNA-seq	97	TCGA
C   GSE270130	Chip-seq	27	Illumina NovaSeq 6000 (Homo sapiens)
GSE224901	RNA-seq	21	Illumina NovaSeq 6000 (Homo sapiens)
C   GSE100400	Chip-seq;RNA-seq;4C_cccDNA	31	Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897	RNA-seq	95	Illumina HiSeq 4000 (Homo sapiens)
GSE262515	RNA-seq	21	Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345	RNA-seq	4	Illumina HiSeq 2500 (Homo sapiens)
C   GSE131257	ATAC-seq;RNA-seq	19	Illumina HiSeq 2500 (Homo sapiens)
GSE94660	RNA-seq	42	Illumina HiSeq 2500 (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE35465 - SENP5 peak across samples

Peak Plot

> Dataset: GSE68402 - SENP5 peak across samples

Peak Plot

> Dataset: GSE270130 - SENP5 peak across samples

Peak Plot

> Dataset: GSE100400 - SENP5 peak across samples

Peak Plot

> Dataset: GSE131257 - SENP5 peak across samples

Peak Plot