Gene Information
|
Gene Name
|
SGK1 |
|
Gene ID
|
6446
|
|
Gene Full Name
|
serum/glucocorticoid regulated kinase 1 |
|
Gene Alias
|
SGK |
|
Transcripts
|
ENSG00000118515
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nuclear speckles; 
|
|
Membrane Info
|
Cancer-related genes, Enzymes, Predicted intracellular proteins |
|
Uniport_ID
|
O00141
|
|
HGNC ID
|
HGNC:10810
|
|
OMIM ID
|
602958 |
|
Summary
|
This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009] |
Target gene [SGK1] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6008650 |
chr6 |
23 |
12 |
8 |
43 |
View |
| 6026136 |
chr6 |
1 |
1 |
0 |
2 |
View |
| 6031510 |
chr6 |
0 |
0 |
0 |
0 |
View |
Target gene [SGK1] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - SGK1 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
