Gene Information
|
Gene Name
|
SPTBN1 |
|
Gene ID
|
6711
|
|
Gene Full Name
|
spectrin beta, non-erythrocytic 1 |
|
Gene Alias
|
DDISBA|ELF|HEL102|SPTB2|betaSpII |
|
Transcripts
|
ENSG00000115306
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Cytosol; 
|
|
Membrane Info
|
Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters |
|
Uniport_ID
|
Q01082
|
|
HGNC ID
|
HGNC:11275
|
|
OMIM ID
|
182790 |
|
Summary
|
Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Target gene [SPTBN1] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6003434 |
chr2 |
126 |
32 |
2 |
160 |
View |
| 6019268 |
chr2 |
6 |
2 |
0 |
8 |
View |
| 6024169 |
chr2 |
3 |
1 |
0 |
4 |
View |
Target gene [SPTBN1] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - SPTBN1 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
