HTLV1 Target gene Detail Information

> SYN3 Gene Search Result


Gene Information
Gene Name SYN3
Gene ID 8224
Gene Full Name synapsin III
Gene Alias -
Transcripts ENSG00000185666
Virus HTLV1
Gene Type protein-coding
HPA Location Info
Membrane Info Plasma proteins, Predicted intracellular proteins
Uniport_ID O14994
HGNC ID HGNC:11496
OMIM ID 602705
Summary This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite direction. Alternative splicing of this gene results in multiple splice variants that encode different isoforms. [provided by RefSeq, Oct 2008]
Target gene [SYN3] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6000673 chr22 8 669 327 1004 View
6000709 chr22 902 35 8 945 View
6001764 chr22 245 42 65 352 View
6003315 chr22 147 21 0 168 View
6004154 chr22 45 54 28 127 View
6010747 chr22 3 7 19 29 View
6013469 chr22 2 5 12 19 View
6013811 chr22 13 2 3 18 View
6015229 chr22 10 3 1 14 View
6019255 chr22 8 0 0 8 View
6020628 chr22 4 2 0 6 View
6023802 chr22 4 0 0 4 View

Target gene [SYN3] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - SYN3 peak across samples

Peak Plot