IV Target gene Detail Information

> TARBP2 Gene Search Result


Gene Information
Gene Name TARBP2
Gene ID 6895
Gene Full Name TARBP2 subunit of RISC loading complex
Gene Alias LOQS|TRBP|TRBP1|TRBP2
Transcripts ENSG00000139546
Virus IV
Gene Type protein-coding
HPA Location Info Nucleoplasm;Nuclear bodies;
Membrane Info Predicted intracellular proteins
Uniport_ID Q15633
HGNC ID HGNC:11569
OMIM ID 605053
Summary HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene. [provided by RefSeq, Jul 2008]
Target gene [TARBP2] related to virus gene/protein/region

Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section


ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 35558132 K41A
NS1
NS
Cell line
G
R
S
T
View
2 35558132 R38A
NS1
NS
Cell line
G
R
S
T
View

Target gene [TARBP2] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE225706
Chip-seq 6 Illumina NovaSeq 6000 (Homo sapiens)
GSE135069 RNA-seq 10 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE113702
Chip-seq 52 Illumina NextSeq 500 (Homo sapiens);Illumina HiSeq 4000 (Homo sapiens)
C
  GSE225704
ATAC-seq 3 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE156060
Chip-seq;RNA-seq 28 Illumina NovaSeq 6000 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE225706 - TARBP2 peak across samples

Peak Plot


> Dataset: GSE113702 - TARBP2 peak across samples

Peak Plot


> Dataset: GSE225704 - TARBP2 peak across samples

Peak Plot


> Dataset: GSE156060 - TARBP2 peak across samples

Peak Plot