Gene Information
|
Gene Name
|
TARBP2 |
|
Gene ID
|
6895
|
|
Gene Full Name
|
TARBP2 subunit of RISC loading complex |
|
Gene Alias
|
LOQS|TRBP|TRBP1|TRBP2 |
|
Transcripts
|
ENSG00000139546
|
|
Virus
|
IV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm;Nuclear bodies;
|
|
Membrane Info
|
Predicted intracellular proteins |
|
Uniport_ID
|
Q15633
|
|
HGNC ID
|
HGNC:11569
|
|
OMIM ID
|
605053 |
|
Summary
|
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene. [provided by RefSeq, Jul 2008] |
Target gene [TARBP2] related to virus gene/protein/region
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
Target gene [TARBP2] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE225706
|
Chip-seq |
6 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE135069
|
RNA-seq |
10 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE113702
|
Chip-seq |
52 |
Illumina NextSeq 500 (Homo sapiens);Illumina HiSeq 4000 (Homo sapiens) |
|
C GSE225704
|
ATAC-seq |
3 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE156060
|
Chip-seq;RNA-seq |
28 |
Illumina NovaSeq 6000 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE225706 - TARBP2 peak across samples
|
Peak Plot
|
> Dataset: GSE113702 - TARBP2 peak across samples
|
Peak Plot
|
> Dataset: GSE225704 - TARBP2 peak across samples
|
Peak Plot
|
> Dataset: GSE156060 - TARBP2 peak across samples
|
Peak Plot
|
|
|