HPV Target gene Detail Information

> TCIM Gene Search Result


Gene Information
Gene Name TCIM
Gene ID 56892
Gene Full Name transcriptional and immune response regulator
Gene Alias C8orf4|TC-1|TC1
Transcripts ENSG00000176907
Virus HPV
Gene Type protein-coding
HPA Location Info Nucleoplasm;Plasma membrane, Cytosol;
Membrane Info Predicted intracellular proteins
Uniport_ID Q9NR00
HGNC ID HGNC:1357
OMIM ID 607702
Summary This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. [provided by RefSeq, Nov 2011]
Target gene [TCIM] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5005491 chr8 1 0 0 1 View

Target gene [TCIM] related to Omics data
Data ID Experiment type Sample number Platform
GSE181805 Expression array 25 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
S
  GSE164690 		scRNA-seq 51 Illumina NextSeq 500 (Homo sapiens)
S
  GSE197461 		scRNA-seq 16 Illumina NovaSeq 6000 (Homo sapiens)
GSE140662 Expression array 8 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
TCGA_CESC DNA methylation sequencing;RNA-seq 288 TCGA
C
  GSE143026 		ATAC-seq;Chip-seq;RNA-seq 30 Illumina HiSeq 2500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a feature/violin plot will be displayed.


> Dataset: GSE164690 - Gene expression in cell subsets

> Dataset: GSE197461 - Gene expression in cell subsets