Gene Information
|
Gene Name
|
TNFRSF9 |
|
Gene ID
|
3604
|
|
Gene Full Name
|
TNF receptor superfamily member 9 |
|
Gene Alias
|
4-1BB|CD137|CDw137|ILA|IMD109 |
|
Transcripts
|
ENSG00000049249
|
|
Virus
|
DENV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Plasma membrane;Nucleoli;
|
|
Membrane Info
|
Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
|
Uniport_ID
|
Q07011
|
|
HGNC ID
|
HGNC:11924
|
|
OMIM ID
|
602250 |
|
Summary
|
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008] |
Target gene [TNFRSF9] related to virus gene/protein/region
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
Target gene [TNFRSF9] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE152255
|
RNA-seq |
99 |
Illumina HiSeq 2000 (Homo sapiens) |
|
GSE155672
|
RNA-seq |
12 |
HiSeq X Ten (Homo sapiens) |
|
C GSE110511
|
Chip-seq |
24 |
Illumina HiSeq 4000 (Homo sapiens) |
|
GSE132367
|
RNA-seq |
57 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE279208
|
RNA-seq |
26 |
DNBSEQ-G400 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE110511 - TNFRSF9 peak across samples
|
Peak Plot
|
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