Gene Information
|
Gene Name
|
TNKS |
|
Gene ID
|
8658
|
|
Gene Full Name
|
tankyrase |
|
Gene Alias
|
ARTD5|PARP-5a|PARP5A|PARPL|TIN1|TINF1|TNKS1|pART5 |
|
Transcripts
|
ENSG00000173273
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm;Nuclear membrane, Nuclear bodies; 
|
|
Membrane Info
|
Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters |
|
Uniport_ID
|
O95271
|
|
HGNC ID
|
HGNC:11941
|
|
OMIM ID
|
603303 |
|
Summary
|
Enables NAD+-protein poly-ADP-ribosyltransferase activity; histone binding activity; and zinc ion binding activity. Involved in several processes, including positive regulation of canonical Wnt signaling pathway; post-translational protein modification; and regulation of chromosome organization. Acts upstream of or within peptidyl-serine phosphorylation and peptidyl-threonine phosphorylation. Located in several cellular components, including chromosome, telomeric region; mitotic spindle pole; and nucleus. [provided by Alliance of Genome Resources, Apr 2025] |
Target gene [TNKS] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6014841 |
chr8 |
15 |
0 |
0 |
15 |
View |
| 6017323 |
chr8 |
8 |
3 |
0 |
11 |
View |
Target gene [TNKS] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - TNKS peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
