Gene Name	UBE2E2
Gene ID	7325
Gene Full Name	ubiquitin conjugating enzyme E2 E2
Gene Alias	UBCH8
Transcripts	ENSG00000182247
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Nucleoplasm;
Membrane Info	Enzymes, Metabolic proteins, Predicted intracellular proteins
Uniport_ID	Q96LR5
HGNC ID	HGNC:12478
OMIM ID	602163
Summary	Enables ISG15 transferase activity and ubiquitin conjugating enzyme activity. Involved in protein modification by small protein conjugation. Acts upstream of or within DNA damage response and positive regulation of G1/S transition of mitotic cell cycle. Predicted to be active in nucleus. Implicated in type 2 diabetes mellitus. [provided by Alliance of Genome Resources, Apr 2025]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6005298	chr3	13	37	41	91	View
6006849	chr3	62	0	1	63	View
6011086	chr3	24	4	0	28	View
6012155	chr3	1	18	4	23	View
6030213	chr3	1	0	0	1	View
6032462	chr3	0	0	0	0	View
6033287	chr3	0	0	0	0	View

Data ID	Experiment type	Sample number	Platform
GSE189602	Methylation profiling (Array)	4	Infinium MethylationEPIC
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789	Expression array	6	NCI/ATC Hs-OperonV3
GSE224047	RNA-seq	10	Illumina NextSeq 500 (Homo sapiens)
GSE168557	Expression array	6	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189	Methylation profiling (Array)	40	Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - UBE2E2 peak across samples

Peak Plot