HTLV1 Target gene Detail Information

> USP53 Gene Search Result


Gene Information
Gene Name USP53
Gene ID 54532
Gene Full Name ubiquitin specific peptidase 53
Gene Alias PFIC7
Transcripts ENSG00000145390
Virus HTLV1
Gene Type protein-coding
HPA Location Info Plasma membrane;Cytosol;
Membrane Info Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins
Uniport_ID Q70EK8
HGNC ID HGNC:29255
OMIM ID 617431
Summary Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in response to auditory stimulus and sensory perception of sound. Predicted to act upstream of or within action potential; epithelial cell apoptotic process; and outer hair cell apoptotic process. Located in bicellular tight junction. Implicated in progressive familial intrahepatic cholestasis. [provided by Alliance of Genome Resources, Apr 2025]
Target gene [USP53] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6013149 chr4 19 1 0 20 View
6020799 chr4 5 1 0 6 View
6024189 chr4 3 0 0 3 View

Target gene [USP53] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - USP53 peak across samples

Peak Plot