Gene symbol: Map2k1

Also known as: Mek1

Organism: Rattus norvegicus

Summary: Enables ATP binding activity; MAP kinase kinase activity; and enzyme binding activity. Involved in several processes, including establishment of vesicle localization; regulation of gene expression; and regulation of intracellular signal transduction. Acts upstream of or within positive regulation of Ras protein signal transduction. Located in several cellular components, including dendrite cytoplasm; perikaryon; and perinuclear region of cytoplasm. Is active in glutamatergic synapse and postsynaptic density. Colocalizes with microtubule. Used to study cataract and prostate adenocarcinoma. Human ortholog(s) of this gene implicated in carcinoma (multiple); cardiofaciocutaneous syndrome 3; high grade glioma; and melorheostosis. Orthologous to human MAP2K1 (mitogen-activated protein kinase kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

NCBI gene ID: 170851 Ensembl:ENSRNOG00000010176 AllianceGenome:RGD:70495


GO Annotation


Category Term ID Term description
Process GO:0000003 Reproduction
Process GO:0000165 MAPK cascade
Process GO:0000278 Mitotic cell cycle
Process GO:0000902 Cell morphogenesis
Process GO:0001568 Blood vessel development
Process GO:0001701 In utero embryonic development
Process GO:0001704 Formation of primary germ layer
Process GO:0001706 Endoderm formation
Process GO:0001890 Placenta development
Process GO:0001892 Embryonic placenta development
Process GO:0001932 Regulation of protein phosphorylation
Process GO:0001934 Positive regulation of protein phosphorylation
Process GO:0001944 Vasculature development
Process GO:0002376 Immune system process
Process GO:0002520 Immune system development
Process GO:0003006 Developmental process involved in reproduction
Process GO:0003008 System process
Process GO:0003013 Circulatory system process
Process GO:0003018 Vascular process in circulatory system
Process GO:0003056 Regulation of vascular associated smooth muscle contraction
Process GO:0006140 Regulation of nucleotide metabolic process
Process GO:0006355 Regulation of transcription, DNA-templated
Process GO:0006357 Regulation of transcription by RNA polymerase II
Process GO:0006468 Protein phosphorylation
Process GO:0006793 Phosphorus metabolic process
Process GO:0006796 Phosphate-containing compound metabolic process
Process GO:0006807 Nitrogen compound metabolic process
Process GO:0006810 Transport
Process GO:0006937 Regulation of muscle contraction
Process GO:0006940 Regulation of smooth muscle contraction
Process GO:0006950 Response to stress
Process GO:0006979 Response to oxidative stress
Process GO:0006996 Organelle organization
Process GO:0007017 Microtubule-based process
Process GO:0007018 Microtubule-based movement
Process GO:0007030 Golgi organization
Process GO:0007049 Cell cycle
Process GO:0007154 Cell communication
Process GO:0007162 Negative regulation of cell adhesion
Process GO:0007165 Signal transduction
Process GO:0007275 Multicellular organism development
Process GO:0007369 Gastrulation
Process GO:0007399 Nervous system development
Process GO:0007417 Central nervous system development
Process GO:0007420 Brain development
Process GO:0007492 Endoderm development
Process GO:0007507 Heart development
Process GO:0008015 Blood circulation
Process GO:0008152 Metabolic process
Process GO:0008283 Cell population proliferation
Process GO:0008285 Negative regulation of cell population proliferation
Process GO:0008544 Epidermis development
Process GO:0009611 Response to wounding
Process GO:0009653 Anatomical structure morphogenesis
Process GO:0009719 Response to endogenous stimulus
Process GO:0009725 Response to hormone
Process GO:0009790 Embryo development
Process GO:0009792 Embryo development ending in birth or egg hatching
Process GO:0009887 Animal organ morphogenesis
Process GO:0009888 Tissue development
Process GO:0009889 Regulation of biosynthetic process
Process GO:0009891 Positive regulation of biosynthetic process
Process GO:0009892 Negative regulation of metabolic process
Process GO:0009893 Positive regulation of metabolic process
Process GO:0009894 Regulation of catabolic process
Process GO:0009896 Positive regulation of catabolic process
Process GO:0009913 Epidermal cell differentiation
Process GO:0009966 Regulation of signal transduction
Process GO:0009967 Positive regulation of signal transduction
Process GO:0009968 Negative regulation of signal transduction
Process GO:0009987 Cellular process
Process GO:0010001 Glial cell differentiation
Process GO:0010033 Response to organic substance
Process GO:0010256 Endomembrane system organization
Process GO:0010468 Regulation of gene expression
Process GO:0010506 Regulation of autophagy
Process GO:0010508 Positive regulation of autophagy
Process GO:0010556 Regulation of macromolecule biosynthetic process
Process GO:0010557 Positive regulation of macromolecule biosynthetic process
Process GO:0010562 Positive regulation of phosphorus metabolic process
Process GO:0010604 Positive regulation of macromolecule metabolic process
Process GO:0010605 Negative regulation of macromolecule metabolic process
Process GO:0010628 Positive regulation of gene expression
Process GO:0010629 Negative regulation of gene expression
Process GO:0010646 Regulation of cell communication
Process GO:0010647 Positive regulation of cell communication
Process GO:0010648 Negative regulation of cell communication
Process GO:0010720 Positive regulation of cell development
Process GO:0010941 Regulation of cell death
Process GO:0010970 Transport along microtubule
Process GO:0010975 Regulation of neuron projection development
Process GO:0014070 Response to organic cyclic compound
Process GO:0016043 Cellular component organization
Process GO:0016310 Phosphorylation
Process GO:0018108 Peptidyl-tyrosine phosphorylation
Process GO:0018193 Peptidyl-amino acid modification
Process GO:0018212 Peptidyl-tyrosine modification
Process GO:0019219 Regulation of nucleobase-containing compound metabolic process
Process GO:0019220 Regulation of phosphate metabolic process
Process GO:0019222 Regulation of metabolic process
Process GO:0019229 Regulation of vasoconstriction
Process GO:0019538 Protein metabolic process
Process GO:0021549 Cerebellum development
Process GO:0021575 Hindbrain morphogenesis
Process GO:0021587 Cerebellum morphogenesis
Process GO:0021695 Cerebellar cortex development
Process GO:0021696 Cerebellar cortex morphogenesis
Process GO:0021697 Cerebellar cortex formation
Process GO:0022008 Neurogenesis
Process GO:0022037 Metencephalon development
Process GO:0022407 Regulation of cell-cell adhesion
Process GO:0022408 Negative regulation of cell-cell adhesion
Process GO:0022414 Reproductive process
Process GO:0022603 Regulation of anatomical structure morphogenesis
Process GO:0023051 Regulation of signaling
Process GO:0023052 Signaling
Process GO:0023056 Positive regulation of signaling
Process GO:0023057 Negative regulation of signaling
Process GO:0030030 Cell projection organization
Process GO:0030154 Cell differentiation
Process GO:0030155 Regulation of cell adhesion
Process GO:0030182 Neuron differentiation
Process GO:0030216 Keratinocyte differentiation
Process GO:0030323 Respiratory tube development
Process GO:0030324 Lung development
Process GO:0030334 Regulation of cell migration
Process GO:0030335 Positive regulation of cell migration
Process GO:0030705 Cytoskeleton-dependent intracellular transport
Process GO:0030808 Regulation of nucleotide biosynthetic process
Process GO:0030810 Positive regulation of nucleotide biosynthetic process
Process GO:0030855 Epithelial cell differentiation
Process GO:0030878 Thyroid gland development
Process GO:0030902 Hindbrain development
Process GO:0031175 Neuron projection development
Process GO:0031323 Regulation of cellular metabolic process
Process GO:0031325 Positive regulation of cellular metabolic process
Process GO:0031326 Regulation of cellular biosynthetic process
Process GO:0031328 Positive regulation of cellular biosynthetic process
Process GO:0031329 Regulation of cellular catabolic process
Process GO:0031331 Positive regulation of cellular catabolic process
Process GO:0031344 Regulation of cell projection organization
Process GO:0031346 Positive regulation of cell projection organization
Process GO:0031399 Regulation of protein modification process
Process GO:0031401 Positive regulation of protein modification process
Process GO:0031960 Response to corticosteroid
Process GO:0032101 Regulation of response to external stimulus
Process GO:0032147 Activation of protein kinase activity
Process GO:0032386 Regulation of intracellular transport
Process GO:0032400 Melanosome localization
Process GO:0032401 Establishment of melanosome localization
Process GO:0032402 Melanosome transport
Process GO:0032501 Multicellular organismal process
Process GO:0032502 Developmental process
Process GO:0032784 Regulation of DNA-templated transcription, elongation
Process GO:0032786 Positive regulation of DNA-templated transcription, elongation
Process GO:0032872 Regulation of stress-activated MAPK cascade
Process GO:0032879 Regulation of localization
Process GO:0032880 Regulation of protein localization
Process GO:0032968 Positive regulation of transcription elongation from RNA polymerase II promoter
Process GO:0032989 Cellular component morphogenesis
Process GO:0032990 Cell part morphogenesis
Process GO:0033043 Regulation of organelle organization
Process GO:0033059 Cellular pigmentation
Process GO:0033500 Carbohydrate homeostasis
Process GO:0033554 Cellular response to stress
Process GO:0033674 Positive regulation of kinase activity
Process GO:0033993 Response to lipid
Process GO:0034110 Regulation of homotypic cell-cell adhesion
Process GO:0034111 Negative regulation of homotypic cell-cell adhesion
Process GO:0034243 Regulation of transcription elongation from RNA polymerase II promoter
Process GO:0035150 Regulation of tube size
Process GO:0035270 Endocrine system development
Process GO:0035295 Tube development
Process GO:0035296 Regulation of tube diameter
Process GO:0035556 Intracellular signal transduction
Process GO:0035987 Endodermal cell differentiation
Process GO:0036211 Protein modification process
Process GO:0040012 Regulation of locomotion
Process GO:0040017 Positive regulation of locomotion
Process GO:0042063 Gliogenesis
Process GO:0042127 Regulation of cell population proliferation
Process GO:0042221 Response to chemical
Process GO:0042325 Regulation of phosphorylation
Process GO:0042327 Positive regulation of phosphorylation
Process GO:0042592 Homeostatic process
Process GO:0042593 Glucose homeostasis
Process GO:0042981 Regulation of apoptotic process
Process GO:0043009 Chordate embryonic development
Process GO:0043066 Negative regulation of apoptotic process
Process GO:0043067 Regulation of programmed cell death
Process GO:0043069 Negative regulation of programmed cell death
Process GO:0043085 Positive regulation of catalytic activity
Process GO:0043087 Regulation of GTPase activity
Process GO:0043170 Macromolecule metabolic process
Process GO:0043408 Regulation of MAPK cascade
Process GO:0043410 Positive regulation of MAPK cascade
Process GO:0043412 Macromolecule modification
Process GO:0043473 Pigmentation
Process GO:0043547 Positive regulation of GTPase activity
Process GO:0043549 Regulation of kinase activity
Process GO:0043588 Skin development
Process GO:0044057 Regulation of system process
Process GO:0044093 Positive regulation of molecular function
Process GO:0044237 Cellular metabolic process
Process GO:0044238 Primary metabolic process
Process GO:0045595 Regulation of cell differentiation
Process GO:0045597 Positive regulation of cell differentiation
Process GO:0045859 Regulation of protein kinase activity
Process GO:0045860 Positive regulation of protein kinase activity
Process GO:0045893 Positive regulation of transcription, DNA-templated
Process GO:0045933 Positive regulation of muscle contraction
Process GO:0045935 Positive regulation of nucleobase-containing compound metabolic process
Process GO:0045937 Positive regulation of phosphate metabolic process
Process GO:0045944 Positive regulation of transcription by RNA polymerase II
Process GO:0045981 Positive regulation of nucleotide metabolic process
Process GO:0046578 Regulation of Ras protein signal transduction
Process GO:0046579 Positive regulation of Ras protein signal transduction
Process GO:0046907 Intracellular transport
Process GO:0047496 Vesicle transport along microtubule
Process GO:0048308 Organelle inheritance
Process GO:0048313 Golgi inheritance
Process GO:0048468 Cell development
Process GO:0048513 Animal organ development
Process GO:0048518 Positive regulation of biological process
Process GO:0048519 Negative regulation of biological process
Process GO:0048522 Positive regulation of cellular process
Process GO:0048523 Negative regulation of cellular process
Process GO:0048534 Hematopoietic or lymphoid organ development
Process GO:0048538 Thymus development
Process GO:0048545 Response to steroid hormone
Process GO:0048568 Embryonic organ development
Process GO:0048583 Regulation of response to stimulus
Process GO:0048584 Positive regulation of response to stimulus
Process GO:0048585 Negative regulation of response to stimulus
Process GO:0048598 Embryonic morphogenesis
Process GO:0048608 Reproductive structure development
Process GO:0048645 Animal organ formation
Process GO:0048646 Anatomical structure formation involved in morphogenesis
Process GO:0048666 Neuron development
Process GO:0048678 Response to axon injury
Process GO:0048679 Regulation of axon regeneration
Process GO:0048699 Generation of neurons
Process GO:0048708 Astrocyte differentiation
Process GO:0048731 System development
Process GO:0048732 Gland development
Process GO:0048812 Neuron projection morphogenesis
Process GO:0048856 Anatomical structure development
Process GO:0048858 Cell projection morphogenesis
Process GO:0048869 Cellular developmental process
Process GO:0048870 Cell motility
Process GO:0048878 Chemical homeostasis
Process GO:0050673 Epithelial cell proliferation
Process GO:0050767 Regulation of neurogenesis
Process GO:0050769 Positive regulation of neurogenesis
Process GO:0050770 Regulation of axonogenesis
Process GO:0050772 Positive regulation of axonogenesis
Process GO:0050789 Regulation of biological process
Process GO:0050790 Regulation of catalytic activity
Process GO:0050793 Regulation of developmental process
Process GO:0050794 Regulation of cellular process
Process GO:0050896 Response to stimulus
Process GO:0051049 Regulation of transport
Process GO:0051056 Regulation of small GTPase mediated signal transduction
Process GO:0051057 Positive regulation of small GTPase mediated signal transduction
Process GO:0051094 Positive regulation of developmental process
Process GO:0051128 Regulation of cellular component organization
Process GO:0051130 Positive regulation of cellular component organization
Process GO:0051171 Regulation of nitrogen compound metabolic process
Process GO:0051173 Positive regulation of nitrogen compound metabolic process
Process GO:0051174 Regulation of phosphorus metabolic process
Process GO:0051179 Localization
Process GO:0051234 Establishment of localization
Process GO:0051239 Regulation of multicellular organismal process
Process GO:0051240 Positive regulation of multicellular organismal process
Process GO:0051246 Regulation of protein metabolic process
Process GO:0051247 Positive regulation of protein metabolic process
Process GO:0051252 Regulation of RNA metabolic process
Process GO:0051254 Positive regulation of RNA metabolic process
Process GO:0051336 Regulation of hydrolase activity
Process GO:0051338 Regulation of transferase activity
Process GO:0051345 Positive regulation of hydrolase activity
Process GO:0051347 Positive regulation of transferase activity
Process GO:0051384 Response to glucocorticoid
Process GO:0051640 Organelle localization
Process GO:0051641 Cellular localization
Process GO:0051648 Vesicle localization
Process GO:0051649 Establishment of localization in cell
Process GO:0051650 Establishment of vesicle localization
Process GO:0051656 Establishment of organelle localization
Process GO:0051716 Cellular response to stimulus
Process GO:0051875 Pigment granule localization
Process GO:0051904 Pigment granule transport
Process GO:0051905 Establishment of pigment granule localization
Process GO:0051960 Regulation of nervous system development
Process GO:0051962 Positive regulation of nervous system development
Process GO:0055088 Lipid homeostasis
Process GO:0055090 Acylglycerol homeostasis
Process GO:0060020 Bergmann glial cell differentiation
Process GO:0060147 Regulation of post-transcriptional gene silencing
Process GO:0060148 Positive regulation of post-transcriptional gene silencing
Process GO:0060255 Regulation of macromolecule metabolic process
Process GO:0060284 Regulation of cell development
Process GO:0060322 Head development
Process GO:0060324 Face development
Process GO:0060341 Regulation of cellular localization
Process GO:0060425 Lung morphogenesis
Process GO:0060428 Lung epithelium development
Process GO:0060429 Epithelium development
Process GO:0060438 Trachea development
Process GO:0060439 Trachea morphogenesis
Process GO:0060440 Trachea formation
Process GO:0060502 Epithelial cell proliferation involved in lung morphogenesis
Process GO:0060541 Respiratory system development
Process GO:0060548 Negative regulation of cell death
Process GO:0060627 Regulation of vesicle-mediated transport
Process GO:0060674 Placenta blood vessel development
Process GO:0060711 Labyrinthine layer development
Process GO:0060964 Regulation of miRNA-mediated gene silencing
Process GO:0060966 Regulation of gene silencing by RNA
Process GO:0061458 Reproductive system development
Process GO:0062012 Regulation of small molecule metabolic process
Process GO:0062013 Positive regulation of small molecule metabolic process
Process GO:0065007 Biological regulation
Process GO:0065008 Regulation of biological quality
Process GO:0065009 Regulation of molecular function
Process GO:0070302 Regulation of stress-activated protein kinase signaling cascade
Process GO:0070328 Triglyceride homeostasis
Process GO:0070371 ERK1 and ERK2 cascade
Process GO:0070372 Regulation of ERK1 and ERK2 cascade
Process GO:0070374 Positive regulation of ERK1 and ERK2 cascade
Process GO:0070570 Regulation of neuron projection regeneration
Process GO:0070920 Regulation of production of small RNA involved in gene silencing by RNA
Process GO:0071704 Organic substance metabolic process
Process GO:0071840 Cellular component organization or biogenesis
Process GO:0071900 Regulation of protein serine/threonine kinase activity
Process GO:0071902 Positive regulation of protein serine/threonine kinase activity
Process GO:0072359 Circulatory system development
Process GO:0072384 Organelle transport along microtubule
Process GO:0080090 Regulation of primary metabolic process
Process GO:0080134 Regulation of response to stress
Process GO:0080135 Regulation of cellular response to stress
Process GO:0090066 Regulation of anatomical structure size
Process GO:0090170 Regulation of Golgi inheritance
Process GO:0090257 Regulation of muscle system process
Process GO:0090398 Cellular senescence
Process GO:0097746 Blood vessel diameter maintenance
Process GO:0098696 Regulation of neurotransmitter receptor localization to postsynaptic specialization membrane
Process GO:0099111 Microtubule-based transport
Process GO:0099518 Vesicle cytoskeletal trafficking
Process GO:0120035 Regulation of plasma membrane bounded cell projection organization
Process GO:0120036 Plasma membrane bounded cell projection organization
Process GO:0120039 Plasma membrane bounded cell projection morphogenesis
Process GO:1900037 Regulation of cellular response to hypoxia
Process GO:1900038 Negative regulation of cellular response to hypoxia
Process GO:1900368 Regulation of post-transcriptional gene silencing by RNA
Process GO:1900370 Positive regulation of post-transcriptional gene silencing by RNA
Process GO:1900371 Regulation of purine nucleotide biosynthetic process
Process GO:1900373 Positive regulation of purine nucleotide biosynthetic process
Process GO:1900542 Regulation of purine nucleotide metabolic process
Process GO:1900544 Positive regulation of purine nucleotide metabolic process
Process GO:1901564 Organonitrogen compound metabolic process
Process GO:1902473 Regulation of protein localization to synapse
Process GO:1902531 Regulation of intracellular signal transduction
Process GO:1902532 Negative regulation of intracellular signal transduction
Process GO:1902533 Positive regulation of intracellular signal transduction
Process GO:1902680 Positive regulation of RNA biosynthetic process
Process GO:1902683 Regulation of receptor localization to synapse
Process GO:1903034 Regulation of response to wounding
Process GO:1903224 Regulation of endodermal cell differentiation
Process GO:1903226 Positive regulation of endodermal cell differentiation
Process GO:1903297 Regulation of hypoxia-induced intrinsic apoptotic signaling pathway
Process GO:1903298 Negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway
Process GO:1903358 Regulation of Golgi organization
Process GO:1903506 Regulation of nucleic acid-templated transcription
Process GO:1903508 Positive regulation of nucleic acid-templated transcription
Process GO:1903522 Regulation of blood circulation
Process GO:1903578 Regulation of ATP metabolic process
Process GO:1903580 Positive regulation of ATP metabolic process
Process GO:1903649 Regulation of cytoplasmic transport
Process GO:1903798 Regulation of miRNA maturation
Process GO:1903800 Positive regulation of miRNA maturation
Process GO:1904375 Regulation of protein localization to cell periphery
Process GO:1905475 Regulation of protein localization to membrane
Process GO:2000026 Regulation of multicellular organismal development
Process GO:2000145 Regulation of cell motility
Process GO:2000147 Positive regulation of cell motility
Process GO:2000637 Positive regulation of miRNA-mediated gene silencing
Process GO:2000641 Regulation of early endosome to late endosome transport
Process GO:2001141 Regulation of RNA biosynthetic process
Process GO:2001169 Regulation of ATP biosynthetic process
Process GO:2001171 Positive regulation of ATP biosynthetic process
Process GO:2001233 Regulation of apoptotic signaling pathway
Process GO:2001234 Negative regulation of apoptotic signaling pathway
Process GO:2001242 Regulation of intrinsic apoptotic signaling pathway
Process GO:2001243 Negative regulation of intrinsic apoptotic signaling pathway
Component GO:0005622 Intracellular anatomical structure
Component GO:0005634 Nucleus
Component GO:0005737 Cytoplasm
Component GO:0005739 Mitochondrion
Component GO:0005768 Endosome
Component GO:0005769 Early endosome
Component GO:0005770 Late endosome
Component GO:0005783 Endoplasmic reticulum
Component GO:0005794 Golgi apparatus
Component GO:0005815 Microtubule organizing center
Component GO:0005829 Cytosol
Component GO:0005856 Cytoskeleton
Component GO:0005886 Plasma membrane
Component GO:0005925 Focal adhesion
Component GO:0005938 Cell cortex
Component GO:0012505 Endomembrane system
Component GO:0014069 Postsynaptic density
Component GO:0015630 Microtubule cytoskeleton
Component GO:0016020 Membrane
Component GO:0030054 Cell junction
Component GO:0030055 Cell-substrate junction
Component GO:0030424 Axon
Component GO:0030425 Dendrite
Component GO:0031410 Cytoplasmic vesicle
Component GO:0031982 Vesicle
Component GO:0032279 Asymmetric synapse
Component GO:0032838 Plasma membrane bounded cell projection cytoplasm
Component GO:0032839 Dendrite cytoplasm
Component GO:0036477 Somatodendritic compartment
Component GO:0042995 Cell projection
Component GO:0043005 Neuron projection
Component GO:0043025 Neuronal cell body
Component GO:0043204 Perikaryon
Component GO:0043226 Organelle
Component GO:0043227 Membrane-bounded organelle
Component GO:0043228 Non-membrane-bounded organelle
Component GO:0043229 Intracellular organelle
Component GO:0043231 Intracellular membrane-bounded organelle
Component GO:0043232 Intracellular non-membrane-bounded organelle
Component GO:0044297 Cell body
Component GO:0045202 Synapse
Component GO:0048471 Perinuclear region of cytoplasm
Component GO:0070161 Anchoring junction
Component GO:0071944 Cell periphery
Component GO:0097447 Dendritic tree
Component GO:0097708 Intracellular vesicle
Component GO:0098794 Postsynapse
Component GO:0098978 Glutamatergic synapse
Component GO:0098984 Neuron to neuron synapse
Component GO:0099568 Cytoplasmic region
Component GO:0099572 Postsynaptic specialization
Component GO:0110165 Cellular anatomical entity
Component GO:0120025 Plasma membrane bounded cell projection
Component GO:0120111 Neuron projection cytoplasm
Function GO:0000166 Nucleotide binding
Function GO:0003824 Catalytic activity
Function GO:0004672 Protein kinase activity
Function GO:0004674 Protein serine/threonine kinase activity
Function GO:0004708 MAP kinase kinase activity
Function GO:0004712 Protein serine/threonine/tyrosine kinase activity
Function GO:0004713 Protein tyrosine kinase activity
Function GO:0005078 MAP-kinase scaffold activity
Function GO:0005488 Binding
Function GO:0005515 Protein binding
Function GO:0005524 ATP binding
Function GO:0008022 Protein C-terminus binding
Function GO:0008047 Enzyme activator activity
Function GO:0016301 Kinase activity
Function GO:0016740 Transferase activity
Function GO:0016772 Transferase activity, transferring phosphorus-containing groups
Function GO:0016773 Phosphotransferase activity, alcohol group as acceptor
Function GO:0017076 Purine nucleotide binding
Function GO:0019207 Kinase regulator activity
Function GO:0019209 Kinase activator activity
Function GO:0019887 Protein kinase regulator activity
Function GO:0019899 Enzyme binding
Function GO:0019900 Kinase binding
Function GO:0019901 Protein kinase binding
Function GO:0030234 Enzyme regulator activity
Function GO:0030295 Protein kinase activator activity
Function GO:0030554 Adenyl nucleotide binding
Function GO:0030674 Protein-macromolecule adaptor activity
Function GO:0031267 Small GTPase binding
Function GO:0031435 Mitogen-activated protein kinase kinase kinase binding
Function GO:0032553 Ribonucleotide binding
Function GO:0032555 Purine ribonucleotide binding
Function GO:0032559 Adenyl ribonucleotide binding
Function GO:0035591 Signaling adaptor activity
Function GO:0035639 Purine ribonucleoside triphosphate binding
Function GO:0036094 Small molecule binding
Function GO:0043167 Ion binding
Function GO:0043168 Anion binding
Function GO:0043539 Protein serine/threonine kinase activator activity
Function GO:0044877 Protein-containing complex binding
Function GO:0047485 Protein N-terminus binding
Function GO:0051020 GTPase binding
Function GO:0060090 Molecular adaptor activity
Function GO:0097110 Scaffold protein binding
Function GO:0097159 Organic cyclic compound binding
Function GO:0097367 Carbohydrate derivative binding
Function GO:0098772 Molecular function regulator activity
Function GO:0106310 Protein serine kinase activity
Function GO:0140096 Catalytic activity, acting on a protein
Function GO:1901265 Nucleoside phosphate binding
Function GO:1901363 Heterocyclic compound binding

Pathway annotation


Category Term ID Term description
RCTM RNO-110056 MAPK3 (ERK1) activation
RCTM RNO-112409 RAF-independent MAPK1/3 activation
RCTM RNO-1266738 Developmental Biology
RCTM RNO-162582 Signal Transduction
RCTM RNO-166520 Signaling by NTRKs
RCTM RNO-169893 Prolonged ERK activation events
RCTM RNO-170968 Frs2-mediated activation
RCTM RNO-187037 Signaling by NTRK1 (TRKA)
RCTM RNO-187687 Signalling to ERKs
RCTM RNO-373760 L1CAM interactions
RCTM RNO-422475 Axon guidance
RCTM RNO-445144 Signal transduction by L1
RCTM RNO-5673000 RAF activation
RCTM RNO-5673001 RAF/MAP kinase cascade
RCTM RNO-5674135 MAP2K and MAPK activation
RCTM RNO-5674499 Negative feedback regulation of MAPK pathway
RCTM RNO-5675221 Negative regulation of MAPK pathway
RCTM RNO-5683057 MAPK family signaling cascades
RCTM RNO-5684996 MAPK1/MAPK3 signaling
RCTM RNO-9006934 Signaling by Receptor Tyrosine Kinases
RCTM RNO-9675108 Nervous system development
WikiPathways WP1279 Estrogen signaling
WikiPathways WP1281 Hypothetical network for drug addiction
WikiPathways WP1284 EPO receptor signaling
WikiPathways WP1299 ErbB signaling pathway
WikiPathways WP1309 Toll-like receptor signaling pathway
WikiPathways WP147 Kit receptor signaling pathway
WikiPathways WP1487 TNF-alpha and mucus production in lung epythelium
WikiPathways WP188 Focal adhesion
WikiPathways WP1968 Genetic alterations of lung cancer
WikiPathways WP2148 Brain derived neurotrophic factor
WikiPathways WP2376 Nuclear factor, erythroid-derived 2, like 2 signaling pathway
WikiPathways WP319 IL-3 signaling pathway
WikiPathways WP351 Regulation of actin cytoskeleton
WikiPathways WP355 IL-1 signaling pathway
WikiPathways WP358 MAPK signaling pathway
WikiPathways WP4268 Ethanol metabolism resulting in production of ROS by CYP2E1
WikiPathways WP439 Insulin signaling
WikiPathways WP569 IL-2 signaling pathway
WikiPathways WP74 Integrin-mediated cell adhesion
WikiPathways WP8 IL-9 signaling pathway
WikiPathways WP94 Hepatocyte growth factor receptor signaling
KEGG rno01521 EGFR tyrosine kinase inhibitor resistance
KEGG rno01522 Endocrine resistance
KEGG rno04010 MAPK signaling pathway
KEGG rno04012 ErbB signaling pathway
KEGG rno04014 Ras signaling pathway
KEGG rno04015 Rap1 signaling pathway
KEGG rno04022 cGMP-PKG signaling pathway
KEGG rno04024 cAMP signaling pathway
KEGG rno04062 Chemokine signaling pathway
KEGG rno04066 HIF-1 signaling pathway
KEGG rno04068 FoxO signaling pathway
KEGG rno04071 Sphingolipid signaling pathway
KEGG rno04072 Phospholipase D signaling pathway
KEGG rno04114 Oocyte meiosis
KEGG rno04140 Autophagy - animal
KEGG rno04148 Efferocytosis
KEGG rno04150 mTOR signaling pathway
KEGG rno04151 PI3K-Akt signaling pathway
KEGG rno04210 Apoptosis
KEGG rno04218 Cellular senescence
KEGG rno04270 Vascular smooth muscle contraction
KEGG rno04370 VEGF signaling pathway
KEGG rno04371 Apelin signaling pathway
KEGG rno04380 Osteoclast differentiation
KEGG rno04510 Focal adhesion
KEGG rno04540 Gap junction
KEGG rno04550 Signaling pathways regulating pluripotency of stem cells
KEGG rno04613 Neutrophil extracellular trap formation
KEGG rno04620 Toll-like receptor signaling pathway
KEGG rno04650 Natural killer cell mediated cytotoxicity
KEGG rno04660 T cell receptor signaling pathway
KEGG rno04662 B cell receptor signaling pathway
KEGG rno04664 Fc epsilon RI signaling pathway
KEGG rno04666 Fc gamma R-mediated phagocytosis
KEGG rno04668 TNF signaling pathway
KEGG rno04720 Long-term potentiation
KEGG rno04722 Neurotrophin signaling pathway
KEGG rno04725 Cholinergic synapse
KEGG rno04726 Serotonergic synapse
KEGG rno04730 Long-term depression
KEGG rno04810 Regulation of actin cytoskeleton
KEGG rno04910 Insulin signaling pathway
KEGG rno04912 GnRH signaling pathway
KEGG rno04914 Progesterone-mediated oocyte maturation
KEGG rno04915 Estrogen signaling pathway
KEGG rno04916 Melanogenesis
KEGG rno04917 Prolactin signaling pathway
KEGG rno04919 Thyroid hormone signaling pathway
KEGG rno04921 Oxytocin signaling pathway
KEGG rno04926 Relaxin signaling pathway
KEGG rno04928 Parathyroid hormone synthesis, secretion and action
KEGG rno04929 GnRH secretion
KEGG rno04934 Cushing syndrome
KEGG rno04935 Growth hormone synthesis, secretion and action
KEGG rno05010 Alzheimer disease
KEGG rno05022 Pathways of neurodegeneration - multiple diseases
KEGG rno05034 Alcoholism
KEGG rno05132 Salmonella infection
KEGG rno05135 Yersinia infection
KEGG rno05160 Hepatitis C
KEGG rno05161 Hepatitis B
KEGG rno05163 Human cytomegalovirus infection
KEGG rno05164 Influenza A
KEGG rno05165 Human papillomavirus infection
KEGG rno05166 Human T-cell leukemia virus 1 infection
KEGG rno05167 Kaposi sarcoma-associated herpesvirus infection
KEGG rno05170 Human immunodeficiency virus 1 infection
KEGG rno05200 Pathways in cancer
KEGG rno05205 Proteoglycans in cancer
KEGG rno05206 MicroRNAs in cancer
KEGG rno05207 Chemical carcinogenesis - receptor activation
KEGG rno05208 Chemical carcinogenesis - reactive oxygen species
KEGG rno05210 Colorectal cancer
KEGG rno05211 Renal cell carcinoma
KEGG rno05212 Pancreatic cancer
KEGG rno05213 Endometrial cancer
KEGG rno05214 Glioma
KEGG rno05215 Prostate cancer
KEGG rno05216 Thyroid cancer
KEGG rno05218 Melanoma
KEGG rno05219 Bladder cancer
KEGG rno05220 Chronic myeloid leukemia
KEGG rno05221 Acute myeloid leukemia
KEGG rno05223 Non-small cell lung cancer
KEGG rno05224 Breast cancer
KEGG rno05225 Hepatocellular carcinoma
KEGG rno05226 Gastric cancer
KEGG rno05230 Central carbon metabolism in cancer
KEGG rno05231 Choline metabolism in cancer
KEGG rno05235 PD-L1 expression and PD-1 checkpoint pathway in cancer

Expression profile of Map2k1 in omics data



ID GSE100499
Title Exploring acupuncture mechanism in preconditioning of IRI
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM2685201 MX1 tissue: Myocardium gender: male 11.966177
GSM2685202 MX2 tissue: Myocardium gender: female 12.014542
GSM2685203 MX3 tissue: Myocardium gender: female 11.8888
GSM2685204 MX4 tissue: Myocardium gender: male 11.613749
GSM2685205 DZ1 tissue: Myocardium gender: male 11.478623
GSM2685206 DZ2 tissue: Myocardium gender: male 12.037105
GSM2685207 DZ3 tissue: Myocardium gender: female 11.984752
GSM2685208 DZ4 tissue: Myocardium gender: female 11.891245
GSM2685209 JJ1 tissue: Myocardium gender: male 12.171345
GSM2685210 JJ2 tissue: Myocardium gender: female 11.818535
GSM2685211 JJ3 tissue: Myocardium gender: female 11.773752
GSM2685212 JJ4 tissue: Myocardium gender: male 11.59662
GSM2685213 NG1 tissue: Myocardium gender: male 11.872009
GSM2685214 NG2 tissue: Myocardium gender: female 12.155381
GSM2685215 NG3 tissue: Myocardium gender: male 11.642545
GSM2685216 NG4 tissue: Myocardium gender: female 11.439524
GSM2685217 YL1 tissue: Myocardium gender: male 11.927086
GSM2685218 YL2 tissue: Myocardium gender: male 11.604513
GSM2685219 YL3 tissue: Myocardium gender: female 12.243923
GSM2685220 YL4 tissue: Myocardium gender: female 11.882476
GSM2685221 QC1 tissue: Myocardium gender: male 11.796243
GSM2685222 QC2 tissue: Myocardium gender: male 11.642545
GSM2685223 QC3 tissue: Myocardium gender: female 12.02509
GSM2685224 QC4 tissue: Myocardium gender: female 11.6225815

ID GSE136833
Title Effects of lidocaine on the expression of rat spinal cord
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4058984 Control_1 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 6.910765643
GSM4058985 Control_2 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 6.919463342
GSM4058986 Control_3 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 6.856704965
GSM4058987 Lidocaine_1 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 6.829799107
GSM4058988 Lidocaine_2 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 6.922505479
GSM4058989 Lidocaine_3 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 6.77001528

ID GSE138454
Title Impact of inflammation on hepatic subcellular energetics in anesthetized rats
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4108997 Sample 1 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 868.0
GSM4108998 Sample 2 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 768.0
GSM4108999 Sample 3 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 1196.0
GSM4109000 Sample 4 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 734.0
GSM4109001 Sample 5 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 816.0
GSM4109002 Sample 6 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 751.0
GSM4109003 Sample 7 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 820.0
GSM4109004 Sample 8 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 1850.0
GSM4109005 Sample9 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 801.0
GSM4109006 Sample10 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 1011.0
GSM4109007 Sample11 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 809.0
GSM4109008 Sample12 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 1444.0
GSM4109009 Sample13 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 669.0
GSM4109010 Sample14 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 696.0
GSM4109011 Sample 15 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 830.0
GSM4109012 Sample16 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 794.0

ID GSE139220
Title Expression data from sevoflurane anesthesia treated rat
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4134285 Brain_Control_rep1 strain: Sprague-Dawley age: 18-month old treatment: control tissue: hippocampus 9.533103
GSM4134286 Brain_Control_rep2 strain: Sprague-Dawley age: 18-month old treatment: control tissue: hippocampus 9.372663
GSM4134287 Brain_Control_rep3 strain: Sprague-Dawley age: 18-month old treatment: control tissue: hippocampus 9.358438
GSM4134288 Brain_Sevoflurane_rep1 strain: Sprague-Dawley age: 18-month old treatment: sevoflurane anesthesia tissue: hippocampus 9.23559
GSM4134289 Brain_Sevoflurane_rep2 strain: Sprague-Dawley age: 18-month old treatment: sevoflurane anesthesia tissue: hippocampus 9.474336
GSM4134290 Brain_Sevoflurane_rep3 strain: Sprague-Dawley age: 18-month old treatment: sevoflurane anesthesia tissue: hippocampus 9.409218

ID GSE143895
Title GPR160 de-orphanization reveals critical roles in neuropathic pain in rodents
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4276356 dhsc01 strain: Sprague Dawley tissue: DHSC treatment: CCI 114.417
GSM4276357 dhsc03 strain: Sprague Dawley tissue: DHSC treatment: CCI 136.884
GSM4276358 dhsc05 strain: Sprague Dawley tissue: DHSC treatment: CCI 114.239
GSM4276359 dhsc13 strain: Sprague Dawley tissue: DHSC treatment: SHAM 120.454
GSM4276360 dhsc15 strain: Sprague Dawley tissue: DHSC treatment: SHAM 115.967

ID GSE157924
Title Regulation of acupuncture on genes in brain stem
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4780973 Rattus_JSSZ(Sham) tissue: Rattus brainstem of modeling treatment: Sham 11.93354109
GSM4780974 Rattus_JXZ(Hand Acu) tissue: Rattus brainstem of modeling treatment: Hand Acu 11.91732672
GSM4780975 Rattus_MXZ(TBI) tissue: Rattus brainstem of modeling treatment: TBI 11.87799286

ID GSE1616
Title Genomics of preconditioning
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM27484 APC_a (anesthetic-preconditioning, 1st replicate) 503.76666666666665
GSM27485 APC_b (anesthetic-preconditioning, 2nd replicate) 409.5
GSM27486 APC_c (anesthetic-preconditioning, 3rd replicate) 499.8666666666666
GSM27487 APC_d (anesthetic-preconditioning, 4th replicate) 515.0666666666667
GSM27488 APC_e (anesthetic-preconditioning, 5th replicate) 569.9
GSM27489 APC_TRI_a (trigger of anesthetic-preconditioning, 1st replicate) 692.1333333333333
GSM27490 APC_TRI_b (trigger of anesthetic-preconditioning, 2nd replicate) 458.56666666666666
GSM27491 APC_TRI_c (trigger of anesthetic-preconditioning, 3rd replicate) 612.6999999999999
GSM27492 APC_TRI_d (trigger of anesthetic-preconditioning, 4th replicate) 482.3666666666666
GSM27493 APC_TRI_e (trigger of anesthetic-preconditioning, 5th replicate) 525.2
GSM27494 CTL_a (control, 1st replicate) 698.1333333333333
GSM27495 CTL_b (control, 2nd replicate) 599.8333333333334
GSM27496 CTL_c (control, 3rd replicate) 561.1333333333333
GSM27497 CTL_d (control, 4th replicate) 635.8000000000001
GSM27498 CTL_e (control, 5th replicate) 628.7333333333333
GSM27499 IPC_a (ischemic preconditioning, 1st replicate) 586.6333333333333
GSM27500 IPC_b (ischemic preconditioning, 2nd replicate) 513.8333333333334
GSM27501 IPC_c (ischemic preconditioning, 3rd replicate) 452.7
GSM27502 IPC_d (ischemic preconditioning, 4th replicate) 464.6666666666667
GSM27503 IPC_e (ischemic preconditioning, 5th replicate) 451.8666666666666
GSM27504 IPC_TRI_a (trigger of ischemic preconditioning, 1st replicate) 655.6333333333333
GSM27505 IPC_TRI_b (trigger of ischemic preconditioning, 2nd replicate) 479.0333333333333
GSM27506 IPC_TRI_c (trigger of ischemic preconditioning, 3rd replicate) 387.0333333333333
GSM27507 IPC_TRI_d (trigger of ischemic preconditioning, 4th replicate) 727.1666666666666
GSM27508 IPC_TRI_e (trigger of ischemic preconditioning, 5th replicate) 366.6333333333334
GSM27509 ISCH_a (ischemia, 1st replicate) 194.20000000000002
GSM27510 ISCH_b (ischemia, 2nd replicate) 559.8000000000001
GSM27511 ISCH_c (ischemia, 3rd replicate) 452.0
GSM27512 ISCH_d (ischemia, 4th replicate) 463.90000000000003
GSM27513 ISCH_e (ischemia, 5th replicate) 443.1666666666667

ID GSE1779
Title Effect of Isoflurane and LTM on basolateral amygdala
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM30790 baseline control 01 male, 275-300g 4199.1
GSM30791 baseline control 02 male, 275-300g 4234.5
GSM30792 baseline control 03 male, 275-300g 4797.2
GSM30793 baseline control 04 male, 275-300g 3825.1
GSM30794 baseline control 05 male, 275-300g 3673.1
GSM30795 baseline control 06 male, 275-300g 4490.7
GSM30796 baseline control 07 male, 275-300g 3928.8
GSM30797 baseline control 08 male, 275-300g 5004.3
GSM30798 baseline control 09 male, 275-300g 4100.3
GSM30799 pain 01 3750.9
GSM30800 pain 02 4842.3
GSM30801 pain 03 3667.5
GSM30802 pain 04 4205.5
GSM30803 pain 05 4439.4
GSM30804 FC 01 3412.2
GSM30805 FC 02 3220.5
GSM30806 FC 03 4127.1
GSM30807 FC 04 4568.7
GSM30808 FC 05 3611.5
GSM30809 IFC 01 3819.9
GSM30810 IFC 02 4073.6
GSM30811 IFC 03 3719.1
GSM30812 IFC 04 4150.7
GSM30813 IFC 05 4414.2
GSM99800 isoflurane 01 male, 275-300g 4800.8
GSM99801 isoflurane 02 male, 275-300g 3922.1
GSM99802 isoflurane 03 male, 275-300g 4731.7
GSM99803 isoflurane 04 male, 275-300g 3594.1
GSM99804 isoflurane 05 male, 275-300g 4102.0

ID GSE190472
Title Study on VEGF regulation mechanism of acupuncture improving endometrial receptivity in IVF-ET
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM5724271 model 21 Sex: female tissue: Uterine tissue condition: model 128.865
GSM5724272 model 22 Sex: female tissue: Uterine tissue condition: model 132.6632
GSM5724273 model 23 Sex: female tissue: Uterine tissue condition: model 132.8958
GSM5724274 treatment31 Sex: female tissue: Uterine tissue condition: treatment 134.722
GSM5724275 treatment32 Sex: female tissue: Uterine tissue condition: treatment 155.2825
GSM5724276 treatment33 Sex: female tissue: Uterine tissue condition: treatment 131.5572
GSM5724277 control 41 Sex: female tissue: Uterine tissue condition: control 192.807
GSM5724278 control 42 Sex: female tissue: Uterine tissue condition: control 192.5106
GSM5724279 control 43 Sex: female tissue: Uterine tissue condition: control 130.2668

ID GSE192399
Title Gene expression of brain regions activated by sevoflurane and propofol
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM5746332 LHb, Sevoflurane, 60mins brain region: the lateral habenula (LHb) treatment: Sevoflurane 12.2219
GSM5746333 LHb, O2, 60mins brain region: the lateral habenula (LHb) treatment: O2 12.2925
GSM5746334 MHb, Sevoflurane, 60mins brain region: the medial habenula (MHb) treatment: Sevoflurane 12.6104
GSM5746335 MHb, O2, 60mins brain region: the medial habenula (MHb) treatment: O2 12.9002
GSM5746336 Sol, Sevoflurane, 60mins brain region: the solitary nucleus (Sol) treatment: Sevoflurane 13.1921
GSM5746337 Sol, O2, 60mins brain region: the solitary nucleus (Sol) treatment: O2 13.438
GSM5746338 Mve, Sevoflurane, 60mins brain region: the medial vestibular nucleus (MVe) treatment: Sevoflurane 12.1641
GSM5746339 Mve, O2, 60mins brain region: the medial vestibular nucleus (MVe) treatment: O2 12.0296
GSM5746340 LHb, Propofol, 60mins brain region: the lateral habenula (LHb) treatment: Propofol 12.4181
GSM5746341 LHb, Intralipos, 60mins brain region: the lateral habenula (LHb) treatment: Intralipos 12.251
GSM5746342 MHb, Propofol, 60mins brain region: the medial habenula (MHb) treatment: Propofol 12.9296
GSM5746343 MHb, Intralipos, 60mins brain region: the medial habenula (MHb) treatment: Intralipos 13.2607
GSM5746344 Sol, Propofol, 60mins brain region: the solitary nucleus (Sol) treatment: Propofol 13.4623
GSM5746345 Sol, Intralipos, 60mins brain region: the solitary nucleus (Sol) treatment: Intralipos 13.032
GSM5746346 MVe, Propofol, 60mins brain region: the medial vestibular nucleus (MVe) treatment: Propofol 12.2811
GSM5746347 MVe, Intralipos, 60mins brain region: the medial vestibular nucleus (MVe) treatment: Intralipos 12.7649

ID GSE205202
Title Hepatic responses of mice and rats to equivalent acetaminophen (APAP) insult [rat]
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM6208507 Rat_Baseline_0h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 9.763793
GSM6208508 Rat_Baseline_0h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 9.758903
GSM6208509 Rat_Baseline_0h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 9.86124
GSM6208510 Rat_Baseline_0h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 9.623044
GSM6208511 Rat_Baseline_0h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 9.614597
GSM6208512 Rat_Vehicle_03h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 9.670839
GSM6208513 Rat_Vehicle_03h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 9.566695
GSM6208514 Rat_Vehicle_03h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 9.574255
GSM6208515 Rat_Vehicle_03h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 9.821274
GSM6208516 Rat_Vehicle_03h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 9.801517
GSM6208517 Rat_Vehicle_06h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 9.772441
GSM6208518 Rat_Vehicle_06h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 9.652016
GSM6208519 Rat_Vehicle_06h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 9.668355
GSM6208520 Rat_Vehicle_06h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 9.612089
GSM6208521 Rat_Vehicle_06h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 9.70402
GSM6208522 Rat_Vehicle_09h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 9.383332
GSM6208523 Rat_Vehicle_09h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 9.453798
GSM6208524 Rat_Vehicle_09h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 9.565667
GSM6208525 Rat_Vehicle_09h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 9.523748
GSM6208526 Rat_Vehicle_09h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 9.688323
GSM6208527 Rat_Vehicle_24h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 9.673067
GSM6208528 Rat_Vehicle_24h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 9.56985
GSM6208529 Rat_Vehicle_24h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 9.515032
GSM6208530 Rat_Vehicle_24h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 9.462235
GSM6208531 Rat_Vehicle_24h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 9.423178
GSM6208532 Rat_APAP_03h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 9.827193
GSM6208533 Rat_APAP_03h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 9.776538
GSM6208534 Rat_APAP_03h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 9.856826
GSM6208535 Rat_APAP_03h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 9.839545
GSM6208536 Rat_APAP_03h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 9.913627
GSM6208537 Rat_APAP_06h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 10.574874
GSM6208538 Rat_APAP_06h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 10.533937
GSM6208539 Rat_APAP_06h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 10.222223
GSM6208540 Rat_APAP_06h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 10.536451
GSM6208541 Rat_APAP_06h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 10.533832
GSM6208542 Rat_APAP_09h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 10.975537
GSM6208543 Rat_APAP_09h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 11.005856
GSM6208544 Rat_APAP_09h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 10.881255
GSM6208545 Rat_APAP_09h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 11.023083
GSM6208546 Rat_APAP_09h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 11.058867
GSM6208547 Rat_APAP_24h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 9.859809
GSM6208548 Rat_APAP_24h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 9.78032
GSM6208549 Rat_APAP_24h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 9.762223
GSM6208550 Rat_APAP_24h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 10.008333
GSM6208551 Rat_APAP_24h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 9.741699

ID GSE232804
Title EGR3 regulates opioid-related nociception and motivation in male rats
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM7383519 ww01_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Salin 3202.0
GSM7383520 ww02_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Saline 3308.0
GSM7383521 ww03_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Salin 3087.0
GSM7383522 ww05_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Saline 2979.0
GSM7383523 ww06_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Salin 3416.0
GSM7383524 ww07_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Saline 2726.0
GSM7383525 ww08_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Salin 3092.0
GSM7383526 ww10_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Saline 2914.0
GSM7383527 ww12_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 2566.0
GSM7383528 ww13_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 4007.0
GSM7383529 ww14_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 3033.0
GSM7383530 ww15_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 3077.0
GSM7383531 ww16_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 2848.0
GSM7383532 ww17_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 3472.0
GSM7383533 ww18_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 3559.0
GSM7383534 ww20_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 2151.0
GSM7383535 ww21_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 2951.0
GSM7383536 ww22_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 3123.0
GSM7383537 ww23_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 2194.0
GSM7383538 ww24_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 2209.0
GSM7383539 ww26_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 3057.0
GSM7383540 ww27_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 4697.0
GSM7383541 ww28_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 3530.0
GSM7383542 ww30_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 2986.0
GSM7383543 ww31_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 2958.0
GSM7383544 ww32_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 1871.0
GSM7383545 ww34_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 2992.0
GSM7383546 ww35_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 3507.0
GSM7383547 ww36_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 3816.0
GSM7383548 ww37_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 4279.0
GSM7383549 ww38_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 3342.0
GSM7383550 www09_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Saline 3835.0
GSM7383551 www19_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 3604.0
GSM7383552 www29_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 3396.0
GSM7383553 www33_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 3632.0
GSM7383554 www39_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 2145.0

ID GSE244436
Title Similarity and dissimilarity in alteration of gene expression profile associated with inhalational anesthesia between sevoflurane and desflurane
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM7816143 Liver, Control for SevoAnes tissue: liver genotype: wild type treatment: Control for SevoAnes 17.285955
GSM7816144 Liver, Anesthetized with sevoflurane for 6 h tissue: liver genotype: wild type treatment: Anesthetized with sevoflurane for 6 h 18.62381
GSM7816145 Liver, Control for DesAnes tissue: liver genotype: wild type treatment: Control for DesAnes 17.613338
GSM7816146 Liver, Anesthetized with desflurane for 6 h tissue: liver genotype: wild type treatment: Anesthetized with desflurane for 6 h 17.481466

ID GSE2982
Title Effect of inhaled anesthetic to cultured cortical neurons
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM61779 Cell Culture Exposure (control1) Cy3 label;Cy5; -0.00552
GSM61796 Cell Culture Exposure (control2) Cy3; Cy5 -0.0137
GSM61797 Cell Culture Exposure (control3) Cy3; Cy5 0.143
GSM61798 Cell Culture Exposure (1MAC Halo1) Cy3; Cy5 -0.0801
GSM61799 Cell Culture Exposure (1MAC Halo2) Cy3; Cy5 0.0374
GSM61800 Cell Culture Exposure (1MAC Halo3) Cy3; Cy5 0.0086
GSM61801 Cell Culture Exposure (3MAC Halo1) Cy3; Cy5 -0.0263
GSM61802 Cell Culture Exposure (3MAC Halo2) Cy3; Cy5 -0.0644
GSM61803 Cell Culture Exposure (3MAC Halo3) Cy3; Cy5 -0.025
GSM61804 Cell Culture Exposure (3MAC ISO1) Cy3; Cy5 0.179
GSM61805 Cell Culture Exposure (3MAC ISO2) Cy3; Cy5 0.131
GSM61806 Cell Culture Exposure (3MAC ISO3) Cy3; Cy5 0.133

ID GSE359
Title Isoflurane Single Exposures
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM5120 Isoflurane single exposure control-1 310.8333333333333
GSM5121 Isoflurane single exposure control-2 482.8666666666666
GSM5122 Isoflurane single exposure control-3 246.83333333333334
GSM5124 Isoflurane single exposure 1 hr-1 199.76666666666665
GSM5126 Isoflurane single exposure 1 hr-2 289.3
GSM5127 Isoflurane single exposure 2 hr-1 507.26666666666665
GSM5130 Isoflurane single exposure 2 hr-2 360.76666666666665
GSM5131 Isoflurane single exposure 2 hr-3 284.3333333333333

ID GSE48025
Title Affymetrix Chip Data of the Transcriptome of the Rheumatoid Arthritis Rat Model Treated with Acupuncture (Affymetrix, mRNA, batch1)
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1165929 RAT_NORA_T0_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats before therapy 9.801341721
GSM1165930 RAT_NORA_T0_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats before therapy 9.726822004
GSM1165931 RAT_RA_T0_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats before therapy 9.663977429
GSM1165932 RAT_RA_T0_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats before therapy 9.57876169
GSM1165933 RAT_NORA_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 1 hour after therapy 9.712127731
GSM1165934 RAT_NORA_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 1 hour after therapy 9.649357546
GSM1165935 RAT_AP_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour acupuncture therapy 9.919571666
GSM1165936 RAT_AP_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour acupuncture therapy 9.464872046
GSM1165937 RAT_MTX_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour MTX therapy 9.61524485
GSM1165938 RAT_MTX_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour MTX therapy 9.585180705
GSM1165939 RAT_ANE_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour ANE therapy 9.370390038
GSM1165940 RAT_ANE_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour ANE therapy 9.548966162
GSM1165941 RAT_PLA_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour placebo therapy 9.646406894
GSM1165942 RAT_PLA_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour placebo therapy 9.957428395
GSM1165943 RAT_NORA_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 34 days after therapy 9.281040893
GSM1165944 RAT_NORA_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 34 days after therapy 9.433710138
GSM1165945 RAT_AP_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days acupuncture therapy 10.39103625
GSM1165946 RAT_AP_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days acupuncture therapy 9.480143122
GSM1165947 RAT_MTX_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days MTX therapy 9.637748441
GSM1165948 RAT_MTX_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days MTX therapy 9.40453306
GSM1165949 RAT_ANE_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days ANE therapy 9.547727627
GSM1165950 RAT_ANE_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days ANE therapy 9.652875646
GSM1165951 RAT_PLA_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days placebo therapy 9.387128601
GSM1165952 RAT_PLA_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days placebo therapy 9.474118082

ID GSE53897
Title Genome-wide analysis of dorsal root ganglion (DRG) gene expression after morphine or oxycodone treatment
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1303240 DRG RVM1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 11.405881
GSM1303241 DRG RVM2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 11.239662
GSM1303242 DRG RVM3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 11.354581
GSM1303243 DRG RVM7 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 11.418926
GSM1303244 DRG RVOx2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 11.278064
GSM1303245 DRG RVOx3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 11.318347
GSM1303246 DRG RVOx5 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 11.379968
GSM1303247 DRG RVOx7 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 11.320068
GSM1303248 DRG RVS4 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 11.322208
GSM1303249 DRG RVS5 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 11.390219
GSM1303250 DRG RVS6 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 11.460669
GSM1303251 DRG RVS7 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 11.33858
GSM1303252 DRG RSM1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 11.305333
GSM1303253 DRG RSM2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 11.367243
GSM1303254 DRG RSM4 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 11.290704
GSM1303255 DRG RSM5 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 11.313333
GSM1303256 DRG RSOx1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 11.240947
GSM1303257 DRG RSOx2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 11.294471
GSM1303258 DRG RSOx3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 11.379968
GSM1303259 DRG RSOx4 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 11.282612
GSM1303260 DRG RSS1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 11.212922
GSM1303261 DRG RSS2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 11.235991
GSM1303262 DRG RSS3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 11.447858
GSM1303263 DRG RSS6 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 11.369571

ID GSE55573
Title Using DNA microarray to screen intracellular signal pathways of hypoglycemic activity by electroacupuncture of Zusanli (ST36) acupoints in streptozotocin-induced rats with diabetes
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1339443 Mock skeletal muscle strain: Wistar age: 8-10 week-old gender: Male 4012.134
GSM1339444 EA (electroacupuncture) skeletal muscle strain: Wistar age: 8-10 week-old gender: Male 4585.346

ID GSE58456
Title Affymetrix Chip Data of the Transcriptome of the Rheumatoid Arthritis Rat Model Treated with Acupuncture (Affymetrix, mRNA, batch 2)
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1693996 Peripheral blood mononuclear cells from NORA before therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 1532.714604
GSM1693997 Peripheral blood mononuclear cells from NORA before therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 2290.551866
GSM1693998 Peripheral blood mononuclear cells from NORA before therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 3039.403216
GSM1693999 Peripheral blood mononuclear cells from RA before therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats before therapy 2090.779008
GSM1694000 Peripheral blood mononuclear cells from RA before therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats before therapy 2211.350263
GSM1694001 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 2179.794387
GSM1694002 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 1993.833478
GSM1694003 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 2480.43901
GSM1694004 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 2427.136208
GSM1694005 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 2540.761649
GSM1694006 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 3194.254421
GSM1694007 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 1616.211998
GSM1694008 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 2051.767436
GSM1694009 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 1758.631432

ID GSE58460
Title Rheumatoid Arthritis Rat Model Treated with Acupuncture
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1165929 RAT_NORA_T0_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats before therapy 9.801341721
GSM1165930 RAT_NORA_T0_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats before therapy 9.726822004
GSM1165931 RAT_RA_T0_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats before therapy 9.663977429
GSM1165932 RAT_RA_T0_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats before therapy 9.57876169
GSM1165933 RAT_NORA_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 1 hour after therapy 9.712127731
GSM1165934 RAT_NORA_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 1 hour after therapy 9.649357546
GSM1165935 RAT_AP_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour acupuncture therapy 9.919571666
GSM1165936 RAT_AP_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour acupuncture therapy 9.464872046
GSM1165937 RAT_MTX_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour MTX therapy 9.61524485
GSM1165938 RAT_MTX_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour MTX therapy 9.585180705
GSM1165939 RAT_ANE_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour ANE therapy 9.370390038
GSM1165940 RAT_ANE_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour ANE therapy 9.548966162
GSM1165941 RAT_PLA_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour placebo therapy 9.646406894
GSM1165942 RAT_PLA_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour placebo therapy 9.957428395
GSM1165943 RAT_NORA_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 34 days after therapy 9.281040893
GSM1165944 RAT_NORA_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 34 days after therapy 9.433710138
GSM1165945 RAT_AP_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days acupuncture therapy 10.39103625
GSM1165946 RAT_AP_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days acupuncture therapy 9.480143122
GSM1165947 RAT_MTX_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days MTX therapy 9.637748441
GSM1165948 RAT_MTX_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days MTX therapy 9.40453306
GSM1165949 RAT_ANE_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days ANE therapy 9.547727627
GSM1165950 RAT_ANE_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days ANE therapy 9.652875646
GSM1165951 RAT_PLA_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days placebo therapy 9.387128601
GSM1165952 RAT_PLA_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days placebo therapy 9.474118082
GSM1412003 RAT_NORA_T0_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412004 RAT_NORA_T0_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412005 RAT_RA_T0_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412006 RAT_RA_T0_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412007 RAT_NORA_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412008 RAT_NORA_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412009 RAT_AP_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412010 RAT_AP_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412011 RAT_MTX_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412012 RAT_MTX_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412013 RAT_ANE_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412014 RAT_ANE_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412015 RAT_PLA_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412016 RAT_PLA_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412017 RAT_NORA_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412018 RAT_NORA_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412019 RAT_AP_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412020 RAT_AP_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412021 RAT_MTX_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412022 RAT_MTX_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412023 RAT_ANE_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412024 RAT_ANE_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412025 RAT_PLA_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412026 RAT_PLA_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412027 RAT_RA_T0_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412028 RAT_RA_T0_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412029 RAT_AP_1h_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412030 RAT_AP_1h_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412031 RAT_PLA_1h_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412032 RAT_PLA_1h_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412033 RAT_AP_34d_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412034 RAT_AP_34d_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412035 RAT_PLA_34d_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412036 RAT_PLA_34d_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1693996 Peripheral blood mononuclear cells from NORA before therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therap 1532.714604
GSM1693997 Peripheral blood mononuclear cells from NORA before therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 2290.551866
GSM1693998 Peripheral blood mononuclear cells from NORA before therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 3039.403216
GSM1693999 Peripheral blood mononuclear cells from RA before therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats before therapy 2090.779008
GSM1694000 Peripheral blood mononuclear cells from RA before therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats before therapy 2211.350263
GSM1694001 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 2179.794387
GSM1694002 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therap 1993.833478
GSM1694003 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 2480.43901
GSM1694004 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 2427.136208
GSM1694005 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 2540.761649
GSM1694006 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 3194.254421
GSM1694007 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 1616.211998
GSM1694008 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 2051.767436
GSM1694009 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 1758.631432

ID GSE752
Title Halothane/Isoflurane Repetitive Exposures
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM5082 Control 1 463.40000000000003
GSM5084 Control 2 517.8333333333334
GSM5085 Control 3 378.2
GSM5086 Control 4 511.2
GSM5087 Control 5 548.9
GSM5090 Control 6 498.26666666666665
GSM5105 Control 7 489.06666666666666
GSM5106 Control 8 455.3333333333333
GSM5107 Control 9 513.1333333333333
GSM5108 Halothane 10 exposure-1 471.1666666666667
GSM5109 Halothane 10 exposures-2 477.3999999999999
GSM5110 Halothane 10 exposures-3 307.90000000000003
GSM5111 Halothane 5 exposures-1 494.43333333333334
GSM5112 Halothane 5 exposures-2 501.76666666666665
GSM5113 Halothane 5 exposures-3 403.5333333333333
GSM5114 Isoflurane 10 exposures-1 414.09999999999997
GSM5115 Isoflurane 10 exposures-2 454.8333333333333
GSM5116 Isoflurane 10 exposures-3 344.23333333333335
GSM5117 Isoflurane 5 exposures-1 523.3333333333334
GSM5118 Isoflurane 5 exposures-2 515.6999999999999
GSM5119 Isoflurane 5 exposures-3 352.86666666666673
GSM11379 Control 10 423.40000000000003
GSM11380 Control 11 431.0
GSM11381 Control 12 449.40000000000003

ID GSE8911
Title Skeletal muscle after fine needle stimulation
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM225891 Skeletal muscle sample from fine needle-stimulated hindlimb Strain: Lewis, Gender: Male, Body Weight: 275g, Tissue: Skeletal muscle sample from fine nnedle-stimulated hindlimb 312.998
GSM225892 Skeletal muscle sample from control hindlimb Strain: Lewis, Gender: Male, Body weight: 275g, Tissue: skeletal muscle sample from non fine needle-stimulated hindlimb 302.494