Gene symbol: Actc1

Organism: Rattus norvegicus

Summary: Predicted to enable ATP binding activity; microfilament motor activity; and myosin binding activity. Involved in cardiac muscle contraction; response to ethanol; and response to xenobiotic stimulus. Predicted to be located in several cellular components, including I band; filopodium; and lamellipodium. Predicted to be part of dynactin complex. Predicted to be active in actin filament; glutamatergic synapse; and sarcomere. Biomarker of hypertension. Human ortholog(s) of this gene implicated in atrial heart septal defect 5; dilated cardiomyopathy; dilated cardiomyopathy 1R; and hypertrophic cardiomyopathy 11. Orthologous to human ACTC1 (actin alpha cardiac muscle 1). [provided by Alliance of Genome Resources, Apr 2022]

NCBI gene ID: 29275 Ensembl:ENSRNOG00000008536 AllianceGenome:RGD:2026


GO Annotation


Category Term ID Term description
Process GO:0003007 Heart morphogenesis
Process GO:0003008 System process
Process GO:0003012 Muscle system process
Process GO:0003013 Circulatory system process
Process GO:0003015 Heart process
Process GO:0006936 Muscle contraction
Process GO:0006941 Striated muscle contraction
Process GO:0006996 Organelle organization
Process GO:0007010 Cytoskeleton organization
Process GO:0007015 Actin filament organization
Process GO:0007275 Multicellular organism development
Process GO:0007507 Heart development
Process GO:0007517 Muscle organ development
Process GO:0008015 Blood circulation
Process GO:0009410 Response to xenobiotic stimulus
Process GO:0009653 Anatomical structure morphogenesis
Process GO:0009887 Animal organ morphogenesis
Process GO:0009888 Tissue development
Process GO:0009893 Positive regulation of metabolic process
Process GO:0009987 Cellular process
Process GO:0010033 Response to organic substance
Process GO:0010468 Regulation of gene expression
Process GO:0010604 Positive regulation of macromolecule metabolic process
Process GO:0010628 Positive regulation of gene expression
Process GO:0010927 Cellular component assembly involved in morphogenesis
Process GO:0010941 Regulation of cell death
Process GO:0014706 Striated muscle tissue development
Process GO:0014866 Skeletal myofibril assembly
Process GO:0016043 Cellular component organization
Process GO:0019222 Regulation of metabolic process
Process GO:0022607 Cellular component assembly
Process GO:0030029 Actin filament-based process
Process GO:0030036 Actin cytoskeleton organization
Process GO:0030048 Actin filament-based movement
Process GO:0030154 Cell differentiation
Process GO:0030239 Myofibril assembly
Process GO:0030240 Skeletal muscle thin filament assembly
Process GO:0031032 Actomyosin structure organization
Process GO:0032501 Multicellular organismal process
Process GO:0032502 Developmental process
Process GO:0032989 Cellular component morphogenesis
Process GO:0033275 Actin-myosin filament sliding
Process GO:0035051 Cardiocyte differentiation
Process GO:0042221 Response to chemical
Process GO:0042692 Muscle cell differentiation
Process GO:0042981 Regulation of apoptotic process
Process GO:0043066 Negative regulation of apoptotic process
Process GO:0043067 Regulation of programmed cell death
Process GO:0043069 Negative regulation of programmed cell death
Process GO:0044085 Cellular component biogenesis
Process GO:0045471 Response to ethanol
Process GO:0048468 Cell development
Process GO:0048513 Animal organ development
Process GO:0048518 Positive regulation of biological process
Process GO:0048519 Negative regulation of biological process
Process GO:0048523 Negative regulation of cellular process
Process GO:0048644 Muscle organ morphogenesis
Process GO:0048646 Anatomical structure formation involved in morphogenesis
Process GO:0048729 Tissue morphogenesis
Process GO:0048731 System development
Process GO:0048738 Cardiac muscle tissue development
Process GO:0048856 Anatomical structure development
Process GO:0048869 Cellular developmental process
Process GO:0050789 Regulation of biological process
Process GO:0050794 Regulation of cellular process
Process GO:0050896 Response to stimulus
Process GO:0051146 Striated muscle cell differentiation
Process GO:0055001 Muscle cell development
Process GO:0055002 Striated muscle cell development
Process GO:0055003 Cardiac myofibril assembly
Process GO:0055006 Cardiac cell development
Process GO:0055007 Cardiac muscle cell differentiation
Process GO:0055008 Cardiac muscle tissue morphogenesis
Process GO:0055013 Cardiac muscle cell development
Process GO:0060047 Heart contraction
Process GO:0060048 Cardiac muscle contraction
Process GO:0060255 Regulation of macromolecule metabolic process
Process GO:0060415 Muscle tissue morphogenesis
Process GO:0060485 Mesenchyme development
Process GO:0060537 Muscle tissue development
Process GO:0060548 Negative regulation of cell death
Process GO:0061061 Muscle structure development
Process GO:0065007 Biological regulation
Process GO:0070252 Actin-mediated cell contraction
Process GO:0070925 Organelle assembly
Process GO:0071840 Cellular component organization or biogenesis
Process GO:0072132 Mesenchyme morphogenesis
Process GO:0072359 Circulatory system development
Process GO:0090130 Tissue migration
Process GO:0090131 Mesenchyme migration
Process GO:0097305 Response to alcohol
Process GO:0097435 Supramolecular fiber organization
Process GO:0140694 Non-membrane-bounded organelle assembly
Process GO:1901700 Response to oxygen-containing compound
Component GO:0005622 Intracellular anatomical structure
Component GO:0005737 Cytoplasm
Component GO:0005856 Cytoskeleton
Component GO:0005869 Dynactin complex
Component GO:0005875 Microtubule associated complex
Component GO:0005884 Actin filament
Component GO:0015629 Actin cytoskeleton
Component GO:0015630 Microtubule cytoskeleton
Component GO:0030016 Myofibril
Component GO:0030017 Sarcomere
Component GO:0030027 Lamellipodium
Component GO:0030054 Cell junction
Component GO:0030175 Filopodium
Component GO:0031252 Cell leading edge
Component GO:0031674 I band
Component GO:0032991 Protein-containing complex
Component GO:0042995 Cell projection
Component GO:0043226 Organelle
Component GO:0043228 Non-membrane-bounded organelle
Component GO:0043229 Intracellular organelle
Component GO:0043232 Intracellular non-membrane-bounded organelle
Component GO:0043292 Contractile fiber
Component GO:0044297 Cell body
Component GO:0045202 Synapse
Component GO:0098858 Actin-based cell projection
Component GO:0098978 Glutamatergic synapse
Component GO:0099080 Supramolecular complex
Component GO:0099081 Supramolecular polymer
Component GO:0099512 Supramolecular fiber
Component GO:0099513 Polymeric cytoskeletal fiber
Component GO:0110165 Cellular anatomical entity
Component GO:0120025 Plasma membrane bounded cell projection
Function GO:0000146 Microfilament motor activity
Function GO:0000166 Nucleotide binding
Function GO:0003774 Cytoskeletal motor activity
Function GO:0005488 Binding
Function GO:0005515 Protein binding
Function GO:0005524 ATP binding
Function GO:0008092 Cytoskeletal protein binding
Function GO:0017022 Myosin binding
Function GO:0017076 Purine nucleotide binding
Function GO:0030554 Adenyl nucleotide binding
Function GO:0032553 Ribonucleotide binding
Function GO:0032555 Purine ribonucleotide binding
Function GO:0032559 Adenyl ribonucleotide binding
Function GO:0035639 Purine ribonucleoside triphosphate binding
Function GO:0036094 Small molecule binding
Function GO:0043167 Ion binding
Function GO:0043168 Anion binding
Function GO:0097159 Organic cyclic compound binding
Function GO:0097367 Carbohydrate derivative binding
Function GO:0140657 ATP-dependent activity
Function GO:1901265 Nucleoside phosphate binding
Function GO:1901363 Heterocyclic compound binding

Pathway annotation


Category Term ID Term description
RCTM RNO-162582 Signal Transduction
RCTM RNO-194315 Signaling by Rho GTPases
RCTM RNO-390522 Striated Muscle Contraction
RCTM RNO-397014 Muscle contraction
RCTM RNO-8980692 RHOA GTPase cycle
RCTM RNO-9012999 RHO GTPase cycle
RCTM RNO-9013026 RHOB GTPase cycle
RCTM RNO-9716542 Signaling by Rho GTPases, Miro GTPases and RHOBTB3
WikiPathways WP140 Myometrial relaxation and contraction pathways
WikiPathways WP2376 Nuclear factor, erythroid-derived 2, like 2 signaling pathway
WikiPathways WP316 Striated muscle contraction
KEGG rno04260 Cardiac muscle contraction
KEGG rno04261 Adrenergic signaling in cardiomyocytes
KEGG rno04814 Motor proteins
KEGG rno04820 Cytoskeleton in muscle cells
KEGG rno05410 Hypertrophic cardiomyopathy
KEGG rno05414 Dilated cardiomyopathy

Expression profile of Actc1 in omics data



ID GSE100499
Title Exploring acupuncture mechanism in preconditioning of IRI
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM2685201 MX1 tissue: Myocardium gender: male 17.824532
GSM2685202 MX2 tissue: Myocardium gender: female 17.824532
GSM2685203 MX3 tissue: Myocardium gender: female 17.800589
GSM2685204 MX4 tissue: Myocardium gender: male 17.863064
GSM2685205 DZ1 tissue: Myocardium gender: male 17.800589
GSM2685206 DZ2 tissue: Myocardium gender: male 17.800589
GSM2685207 DZ3 tissue: Myocardium gender: female 17.800589
GSM2685208 DZ4 tissue: Myocardium gender: female 17.800589
GSM2685209 JJ1 tissue: Myocardium gender: male 17.712673
GSM2685210 JJ2 tissue: Myocardium gender: female 17.684639
GSM2685211 JJ3 tissue: Myocardium gender: female 17.712673
GSM2685212 JJ4 tissue: Myocardium gender: male 17.655949
GSM2685213 NG1 tissue: Myocardium gender: male 17.863064
GSM2685214 NG2 tissue: Myocardium gender: female 17.800589
GSM2685215 NG3 tissue: Myocardium gender: male 17.579271
GSM2685216 NG4 tissue: Myocardium gender: female 17.77291
GSM2685217 YL1 tissue: Myocardium gender: male 17.824532
GSM2685218 YL2 tissue: Myocardium gender: male 17.824532
GSM2685219 YL3 tissue: Myocardium gender: female 17.345846
GSM2685220 YL4 tissue: Myocardium gender: female 17.540442
GSM2685221 QC1 tissue: Myocardium gender: male 17.863064
GSM2685222 QC2 tissue: Myocardium gender: male 17.77291
GSM2685223 QC3 tissue: Myocardium gender: female 17.712673
GSM2685224 QC4 tissue: Myocardium gender: female 17.824532

ID GSE136833
Title Effects of lidocaine on the expression of rat spinal cord
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4058984 Control_1 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 3.230333974
GSM4058985 Control_2 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 3.038661994
GSM4058986 Control_3 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 3.085667619
GSM4058987 Lidocaine_1 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 3.170379602
GSM4058988 Lidocaine_2 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 3.206944171
GSM4058989 Lidocaine_3 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 3.256238095

ID GSE138454
Title Impact of inflammation on hepatic subcellular energetics in anesthetized rats
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4108997 Sample 1 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 0.0
GSM4108998 Sample 2 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 0.0
GSM4108999 Sample 3 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 0.0
GSM4109000 Sample 4 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 0.0
GSM4109001 Sample 5 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 1.0
GSM4109002 Sample 6 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 0.0
GSM4109003 Sample 7 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 0.0
GSM4109004 Sample 8 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 0.0
GSM4109005 Sample9 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 0.0
GSM4109006 Sample10 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 0.0
GSM4109007 Sample11 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 0.0
GSM4109008 Sample12 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 0.0
GSM4109009 Sample13 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 0.0
GSM4109010 Sample14 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 0.0
GSM4109011 Sample 15 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 0.0
GSM4109012 Sample16 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 0.0

ID GSE139220
Title Expression data from sevoflurane anesthesia treated rat
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4134285 Brain_Control_rep1 strain: Sprague-Dawley age: 18-month old treatment: control tissue: hippocampus 5.402758
GSM4134286 Brain_Control_rep2 strain: Sprague-Dawley age: 18-month old treatment: control tissue: hippocampus 5.544232
GSM4134287 Brain_Control_rep3 strain: Sprague-Dawley age: 18-month old treatment: control tissue: hippocampus 5.455418
GSM4134288 Brain_Sevoflurane_rep1 strain: Sprague-Dawley age: 18-month old treatment: sevoflurane anesthesia tissue: hippocampus 5.611279
GSM4134289 Brain_Sevoflurane_rep2 strain: Sprague-Dawley age: 18-month old treatment: sevoflurane anesthesia tissue: hippocampus 5.428009
GSM4134290 Brain_Sevoflurane_rep3 strain: Sprague-Dawley age: 18-month old treatment: sevoflurane anesthesia tissue: hippocampus 5.322889

ID GSE143895
Title GPR160 de-orphanization reveals critical roles in neuropathic pain in rodents
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4276356 dhsc01 strain: Sprague Dawley tissue: DHSC treatment: CCI 0.426
GSM4276357 dhsc03 strain: Sprague Dawley tissue: DHSC treatment: CCI 0.559
GSM4276358 dhsc05 strain: Sprague Dawley tissue: DHSC treatment: CCI 0.247
GSM4276359 dhsc13 strain: Sprague Dawley tissue: DHSC treatment: SHAM 0.501
GSM4276360 dhsc15 strain: Sprague Dawley tissue: DHSC treatment: SHAM 0.453

ID GSE1616
Title Genomics of preconditioning
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM27484 APC_a (anesthetic-preconditioning, 1st replicate) 35668.2
GSM27485 APC_b (anesthetic-preconditioning, 2nd replicate) 40514.3
GSM27486 APC_c (anesthetic-preconditioning, 3rd replicate) 43106.6
GSM27487 APC_d (anesthetic-preconditioning, 4th replicate) 42149.6
GSM27488 APC_e (anesthetic-preconditioning, 5th replicate) 24346.7
GSM27489 APC_TRI_a (trigger of anesthetic-preconditioning, 1st replicate) 56973.0
GSM27490 APC_TRI_b (trigger of anesthetic-preconditioning, 2nd replicate) 59288.8
GSM27491 APC_TRI_c (trigger of anesthetic-preconditioning, 3rd replicate) 49252.1
GSM27492 APC_TRI_d (trigger of anesthetic-preconditioning, 4th replicate) 59644.0
GSM27493 APC_TRI_e (trigger of anesthetic-preconditioning, 5th replicate) 68862.1
GSM27494 CTL_a (control, 1st replicate) 31379.2
GSM27495 CTL_b (control, 2nd replicate) 48227.2
GSM27496 CTL_c (control, 3rd replicate) 53738.9
GSM27497 CTL_d (control, 4th replicate) 27440.0
GSM27498 CTL_e (control, 5th replicate) 34229.9
GSM27499 IPC_a (ischemic preconditioning, 1st replicate) 28061.1
GSM27500 IPC_b (ischemic preconditioning, 2nd replicate) 37642.0
GSM27501 IPC_c (ischemic preconditioning, 3rd replicate) 34298.3
GSM27502 IPC_d (ischemic preconditioning, 4th replicate) 34964.7
GSM27503 IPC_e (ischemic preconditioning, 5th replicate) 52852.8
GSM27504 IPC_TRI_a (trigger of ischemic preconditioning, 1st replicate) 44585.0
GSM27505 IPC_TRI_b (trigger of ischemic preconditioning, 2nd replicate) 79637.0
GSM27506 IPC_TRI_c (trigger of ischemic preconditioning, 3rd replicate) 70126.0
GSM27507 IPC_TRI_d (trigger of ischemic preconditioning, 4th replicate) 68343.2
GSM27508 IPC_TRI_e (trigger of ischemic preconditioning, 5th replicate) 89295.8
GSM27509 ISCH_a (ischemia, 1st replicate) 118160.7
GSM27510 ISCH_b (ischemia, 2nd replicate) 44685.3
GSM27511 ISCH_c (ischemia, 3rd replicate) 50074.1
GSM27512 ISCH_d (ischemia, 4th replicate) 44876.6
GSM27513 ISCH_e (ischemia, 5th replicate) 43288.8

ID GSE192399
Title Gene expression of brain regions activated by sevoflurane and propofol
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM5746332 LHb, Sevoflurane, 60mins brain region: the lateral habenula (LHb) treatment: Sevoflurane 4.64902
GSM5746333 LHb, O2, 60mins brain region: the lateral habenula (LHb) treatment: O2 4.83326
GSM5746334 MHb, Sevoflurane, 60mins brain region: the medial habenula (MHb) treatment: Sevoflurane 4.90311
GSM5746335 MHb, O2, 60mins brain region: the medial habenula (MHb) treatment: O2 5.05437
GSM5746336 Sol, Sevoflurane, 60mins brain region: the solitary nucleus (Sol) treatment: Sevoflurane 4.88419
GSM5746337 Sol, O2, 60mins brain region: the solitary nucleus (Sol) treatment: O2 5.0832
GSM5746338 Mve, Sevoflurane, 60mins brain region: the medial vestibular nucleus (MVe) treatment: Sevoflurane 4.64654
GSM5746339 Mve, O2, 60mins brain region: the medial vestibular nucleus (MVe) treatment: O2 4.79351
GSM5746340 LHb, Propofol, 60mins brain region: the lateral habenula (LHb) treatment: Propofol 5.25769
GSM5746341 LHb, Intralipos, 60mins brain region: the lateral habenula (LHb) treatment: Intralipos 5.26032
GSM5746342 MHb, Propofol, 60mins brain region: the medial habenula (MHb) treatment: Propofol 5.69706
GSM5746343 MHb, Intralipos, 60mins brain region: the medial habenula (MHb) treatment: Intralipos 5.38637
GSM5746344 Sol, Propofol, 60mins brain region: the solitary nucleus (Sol) treatment: Propofol 5.39648
GSM5746345 Sol, Intralipos, 60mins brain region: the solitary nucleus (Sol) treatment: Intralipos 5.39716
GSM5746346 MVe, Propofol, 60mins brain region: the medial vestibular nucleus (MVe) treatment: Propofol 4.96396
GSM5746347 MVe, Intralipos, 60mins brain region: the medial vestibular nucleus (MVe) treatment: Intralipos 5.57538

ID GSE205202
Title Hepatic responses of mice and rats to equivalent acetaminophen (APAP) insult [rat]
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM6208507 Rat_Baseline_0h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 6.011444
GSM6208508 Rat_Baseline_0h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 6.144368
GSM6208509 Rat_Baseline_0h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 6.018697
GSM6208510 Rat_Baseline_0h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 6.054955
GSM6208511 Rat_Baseline_0h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 6.154957
GSM6208512 Rat_Vehicle_03h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 6.37033
GSM6208513 Rat_Vehicle_03h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 6.40191
GSM6208514 Rat_Vehicle_03h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 6.371716
GSM6208515 Rat_Vehicle_03h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 6.35054
GSM6208516 Rat_Vehicle_03h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 6.467201
GSM6208517 Rat_Vehicle_06h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 6.209226
GSM6208518 Rat_Vehicle_06h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 6.478114
GSM6208519 Rat_Vehicle_06h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 6.402129
GSM6208520 Rat_Vehicle_06h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 6.31564
GSM6208521 Rat_Vehicle_06h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 6.404383
GSM6208522 Rat_Vehicle_09h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 6.163299
GSM6208523 Rat_Vehicle_09h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 6.225002
GSM6208524 Rat_Vehicle_09h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 6.325575
GSM6208525 Rat_Vehicle_09h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 6.12653
GSM6208526 Rat_Vehicle_09h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 6.158836
GSM6208527 Rat_Vehicle_24h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 5.819896
GSM6208528 Rat_Vehicle_24h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 6.112957
GSM6208529 Rat_Vehicle_24h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 6.163893
GSM6208530 Rat_Vehicle_24h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 6.163893
GSM6208531 Rat_Vehicle_24h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 6.101023
GSM6208532 Rat_APAP_03h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 6.099189
GSM6208533 Rat_APAP_03h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 6.186433
GSM6208534 Rat_APAP_03h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 6.157778
GSM6208535 Rat_APAP_03h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 6.09257
GSM6208536 Rat_APAP_03h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 6.123436
GSM6208537 Rat_APAP_06h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 6.008517
GSM6208538 Rat_APAP_06h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 6.164012
GSM6208539 Rat_APAP_06h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 6.120235
GSM6208540 Rat_APAP_06h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 6.094282
GSM6208541 Rat_APAP_06h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 6.163893
GSM6208542 Rat_APAP_09h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 6.267596
GSM6208543 Rat_APAP_09h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 6.083011
GSM6208544 Rat_APAP_09h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 6.09397
GSM6208545 Rat_APAP_09h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 6.273672
GSM6208546 Rat_APAP_09h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 6.232664
GSM6208547 Rat_APAP_24h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 6.388496
GSM6208548 Rat_APAP_24h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 6.206319
GSM6208549 Rat_APAP_24h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 5.807227
GSM6208550 Rat_APAP_24h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 6.153189
GSM6208551 Rat_APAP_24h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 6.187435

ID GSE2982
Title Effect of inhaled anesthetic to cultured cortical neurons
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM61779 Cell Culture Exposure (control1) Cy3 label;Cy5; 0.143
GSM61796 Cell Culture Exposure (control2) Cy3; Cy5 0.192
GSM61797 Cell Culture Exposure (control3) Cy3; Cy5 0.0
GSM61798 Cell Culture Exposure (1MAC Halo1) Cy3; Cy5 0.0
GSM61799 Cell Culture Exposure (1MAC Halo2) Cy3; Cy5 0.0
GSM61800 Cell Culture Exposure (1MAC Halo3) Cy3; Cy5 -0.0834
GSM61801 Cell Culture Exposure (3MAC Halo1) Cy3; Cy5 0.0
GSM61802 Cell Culture Exposure (3MAC Halo2) Cy3; Cy5 0.0472
GSM61803 Cell Culture Exposure (3MAC Halo3) Cy3; Cy5 0.0
GSM61804 Cell Culture Exposure (3MAC ISO1) Cy3; Cy5 0.0
GSM61805 Cell Culture Exposure (3MAC ISO2) Cy3; Cy5 0.0
GSM61806 Cell Culture Exposure (3MAC ISO3) Cy3; Cy5 0.0

ID GSE359
Title Isoflurane Single Exposures
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM5120 Isoflurane single exposure control-1 22.8
GSM5121 Isoflurane single exposure control-2 8.3
GSM5122 Isoflurane single exposure control-3 6.3
GSM5124 Isoflurane single exposure 1 hr-1 9.3
GSM5126 Isoflurane single exposure 1 hr-2 4.5
GSM5127 Isoflurane single exposure 2 hr-1 5.3
GSM5130 Isoflurane single exposure 2 hr-2 7.7
GSM5131 Isoflurane single exposure 2 hr-3 4.6

ID GSE53897
Title Genome-wide analysis of dorsal root ganglion (DRG) gene expression after morphine or oxycodone treatment
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1303240 DRG RVM1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.737125
GSM1303241 DRG RVM2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.629799
GSM1303242 DRG RVM3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.809898
GSM1303243 DRG RVM7 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.706417
GSM1303244 DRG RVOx2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.649272
GSM1303245 DRG RVOx3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.615093
GSM1303246 DRG RVOx5 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.662143
GSM1303247 DRG RVOx7 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.757841
GSM1303248 DRG RVS4 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.659707
GSM1303249 DRG RVS5 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.780505
GSM1303250 DRG RVS6 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.723087
GSM1303251 DRG RVS7 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.709953
GSM1303252 DRG RSM1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.702735
GSM1303253 DRG RSM2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.607249
GSM1303254 DRG RSM4 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.787835
GSM1303255 DRG RSM5 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.739988
GSM1303256 DRG RSOx1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.71
GSM1303257 DRG RSOx2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.777706
GSM1303258 DRG RSOx3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.666878
GSM1303259 DRG RSOx4 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.733346
GSM1303260 DRG RSS1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.739053
GSM1303261 DRG RSS2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.793181
GSM1303262 DRG RSS3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.728305
GSM1303263 DRG RSS6 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.639045

ID GSE55573
Title Using DNA microarray to screen intracellular signal pathways of hypoglycemic activity by electroacupuncture of Zusanli (ST36) acupoints in streptozotocin-induced rats with diabetes
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1339443 Mock skeletal muscle strain: Wistar age: 8-10 week-old gender: Male 147.2642
GSM1339444 EA (electroacupuncture) skeletal muscle strain: Wistar age: 8-10 week-old gender: Male 145.6627

ID GSE752
Title Halothane/Isoflurane Repetitive Exposures
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM5082 Control 1 6.2
GSM5084 Control 2 4.7
GSM5085 Control 3 6.1
GSM5086 Control 4 7.8
GSM5087 Control 5 8.5
GSM5090 Control 6 6.6
GSM5105 Control 7 3.1
GSM5106 Control 8 7.8
GSM5107 Control 9 7.0
GSM5108 Halothane 10 exposure-1 5.3
GSM5109 Halothane 10 exposures-2 5.4
GSM5110 Halothane 10 exposures-3 9.8
GSM5111 Halothane 5 exposures-1 7.6
GSM5112 Halothane 5 exposures-2 5.2
GSM5113 Halothane 5 exposures-3 6.5
GSM5114 Isoflurane 10 exposures-1 4.5
GSM5115 Isoflurane 10 exposures-2 10.7
GSM5116 Isoflurane 10 exposures-3 5.6
GSM5117 Isoflurane 5 exposures-1 5.8
GSM5118 Isoflurane 5 exposures-2 7.7
GSM5119 Isoflurane 5 exposures-3 6.4
GSM11379 Control 10 9.5
GSM11380 Control 11 6.1
GSM11381 Control 12 7.6