Gene Name	APBA2
Gene ID	321
Gene Full Name	amyloid beta precursor protein binding family A member 2
Gene Alias	D15S1518E|HsT16821|LIN-10|MGC:14091|MINT2|X11-BETA|X11L
Transcripts	ENSG00000034053
Virus	HBV
Gene Type	protein-coding
HPA Location Info	Golgi apparatus;
Membrane Info	Predicted intracellular proteins, Transporters
Uniport_ID	Q99767
HGNC ID	HGNC:579
OMIM ID	602712
Summary	The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2017]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1006981	chr15	26	3	2	31	View
1011654	chr15	8	0	0	8	View
1013558	chr15	4	1	0	5	View
1022036	chr15	26	3	2	31	View
1024147	chr15	4	0	0	4	View
1042114	chr15	1	2	5	8	View

Data ID	Experiment type	Sample number	Platform
GSE252863	scRNA-seq	10	Illumina HiSeq 2500 (Homo sapiens)
GSE236281	RNA-seq	12	Illumina MiSeq (Homo sapiens)
C   GSE35465	Chip-seq;RNA-seq	6	Illumina HiSeq 2000 (Homo sapiens)
C   GSE68402	Chip-seq	26	Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
GSE247322	scRNA-seq	27	Illumina NovaSeq 6000 (Homo sapiens)
TCGA_LIHC_HBV	DNA methylation sequencing;RNA-seq	97	TCGA
C   GSE270130	Chip-seq	27	Illumina NovaSeq 6000 (Homo sapiens)
GSE224901	RNA-seq	21	Illumina NovaSeq 6000 (Homo sapiens)
C   GSE100400	Chip-seq;RNA-seq;4C_cccDNA	31	Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897	RNA-seq	95	Illumina HiSeq 4000 (Homo sapiens)
GSE262515	RNA-seq	21	Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345	RNA-seq	4	Illumina HiSeq 2500 (Homo sapiens)
C   GSE131257	ATAC-seq;RNA-seq	19	Illumina HiSeq 2500 (Homo sapiens)
GSE94660	RNA-seq	42	Illumina HiSeq 2500 (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE35465 - APBA2 peak across samples

Peak Plot

> Dataset: GSE68402 - APBA2 peak across samples

Peak Plot

> Dataset: GSE270130 - APBA2 peak across samples

Peak Plot

> Dataset: GSE100400 - APBA2 peak across samples

Peak Plot

> Dataset: GSE131257 - APBA2 peak across samples

Peak Plot