HPV Target gene Detail Information

> APELA Gene Search Result


Gene Information
Gene Name APELA
Gene ID 100506013
Gene Full Name apelin receptor early endogenous ligand
Gene Alias ELA|Ende|tdl
Transcripts ENSG00000248329
Virus HPV
Gene Type protein-coding
HPA Location Info Secreted in other tissues;
Membrane Info Predicted secreted proteins
Uniport_ID P0DMC3
HGNC ID HGNC:48925
OMIM ID 615594
Summary This gene encodes a peptide hormone that binds to the Apelin receptor. The encoded protein is required for heart development in zebrafish and has been shown to maintain self-renewal of human embryonic stem cells through activation of the PI3K/AKT pathway. Experiments in human and mouse cell lines point to additional roles for the encoded protein in angiogenesis and regulation of vascular tone. [provided by RefSeq, Jul 2016]
Target gene [APELA] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5005571 chr4 4 3 0 7 View

Target gene [APELA] related to Omics data
Data ID Experiment type Sample number Platform
GSE169622 Methylation profiling (Array) 9 Infinium MethylationEPIC
GSE181805 Expression array 25 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215 RNA-seq 8 Illumina NovaSeq 6000 (Homo sapiens)
GSE140662 Expression array 8 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
TCGA_CESC DNA methylation sequencing;RNA-seq 288 TCGA
C
  GSE143026 		ATAC-seq;Chip-seq;RNA-seq 30 Illumina HiSeq 2500 (Homo sapiens)
GSE165883 RNA-seq 20 Illumina NextSeq 500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE143026 - APELA peak across samples

Peak Plot