HBV Target gene Detail Information

> APOC2 Gene Search Result


Gene Information
Gene Name APOC2
Gene ID 344
Gene Full Name apolipoprotein C2
Gene Alias APO-CII|APOC-II
Transcripts ENSG00000234906
Virus HBV
Gene Type protein-coding
HPA Location Info Secreted to blood;
Membrane Info Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins
Uniport_ID P02655
HGNC ID HGNC:609
OMIM ID 608083
Summary This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene. [provided by RefSeq, Mar 2011]
Target gene [APOC2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1039603 chr19 17 10 6 33 View
1039604 chr19 20 10 6 36 View
1039605 chr19 48 27 36 111 View
1039606 chr19 49 27 36 112 View
1039607 chr19 50 27 36 113 View
1039608 chr19 52 27 36 115 View
1039609 chr19 52 12 5 69 View
1039610 chr19 52 12 5 69 View
1039611 chr19 52 13 6 71 View
1039612 chr19 49 11 4 64 View
1039613 chr19 49 11 4 64 View
1039614 chr19 49 11 4 64 View

Target gene [APOC2] related to Omics data
Data ID Experiment type Sample number Platform
S
  GSE252863 		scRNA-seq 10 Illumina HiSeq 2500 (Homo sapiens)
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
S
  GSE247322 		scRNA-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130 		Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
E
  GSE100400 		Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
GSE131257 ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
GSE94660 RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE100400 - APOC2 expression across samples

Volcano Plot

Bar Plot