HBV Target gene Detail Information

> APOC3 Gene Search Result


Gene Information
Gene Name APOC3
Gene ID 345
Gene Full Name apolipoprotein C3
Gene Alias APOCIII|Apo-C3|ApoC-3
Transcripts ENSG00000110245
Virus HBV
Gene Type protein-coding
HPA Location Info Nucleoplasm;Nucleoli, Cell Junctions;Secreted to blood;
Membrane Info Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins
Uniport_ID P02656
HGNC ID HGNC:610
OMIM ID 107720
Summary This gene encodes a protein component of triglyceride (TG)-rich lipoproteins (TRLs) including very low density lipoproteins (VLDL), high density lipoproteins (HDL) and chylomicrons. The encoded protein plays a role in role in the metabolism of these TRLs through multiple modes. This protein has been shown to promote the secretion of VLDL1, inhibit lipoprotein lipase enzyme activity, and delay catabolism of TRL remnants. Mutations in this gene are associated with low plasma triglyceride levels and reduced risk of ischemic cardiovascular disease, and hyperalphalipoproteinemia, which is characterized by elevated levels of high density lipoprotein (HDL) and HDL cholesterol in human patients. This gene and other related genes comprise an apolipoprotein gene cluster on chromosome 11. [provided by RefSeq, Sep 2017]
Target gene [APOC3] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005195 chr11 30 29 0 59 View
1007724 chr11 11 14 0 25 View
1010833 chr11 9 2 0 11 View
1011056 chr11 4 6 0 10 View
1039067 chr11 31 22 0 53 View
1039068 chr11 20 5 0 25 View
1039069 chr11 21 5 0 26 View
1039070 chr11 22 5 0 27 View
1039071 chr11 22 5 0 27 View
1039072 chr11 23 7 0 30 View
1039073 chr11 24 8 0 32 View
1039074 chr11 24 8 0 32 View
1039075 chr11 14 3 0 17 View
1039076 chr11 14 3 0 17 View
1039077 chr11 14 3 0 17 View
1039078 chr11 14 3 0 17 View
1039079 chr11 14 3 0 17 View
1039080 chr11 14 3 0 17 View
1039081 chr11 14 3 0 17 View
1039082 chr11 14 3 0 17 View
1039083 chr11 14 3 0 17 View
1039084 chr11 14 3 0 17 View
1039085 chr11 14 3 0 17 View
1039086 chr11 14 3 0 17 View
1039087 chr11 14 3 0 17 View
1039088 chr11 14 3 0 17 View
1039089 chr11 14 3 0 17 View
1039090 chr11 14 3 0 17 View
1039091 chr11 14 3 0 17 View

Target gene [APOC3] related to Omics data
Data ID Experiment type Sample number Platform
S
  GSE252863 		scRNA-seq 10 Illumina HiSeq 2500 (Homo sapiens)
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
C
  GSE35465 		Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
GSE199850 scRNA-seq 1 HiSeq X Ten (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
S
  GSE247322 		scRNA-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130 		Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
E
  GSE100400 		Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
E
  GSE94660 		RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE100400 - APOC3 expression across samples

Volcano Plot

Bar Plot

> Dataset: GSE94660 - APOC3 expression across samples

Volcano Plot

Bar Plot