HTLV1 Target gene Detail Information

> CDC42BPA Gene Search Result


Gene Information
Gene Name CDC42BPA
Gene ID 8476
Gene Full Name CDC42 binding protein kinase alpha
Gene Alias MRCK|MRCKA|MRCKalpha|PK428
Transcripts ENSG00000143776
Virus HTLV1
Gene Type protein-coding
HPA Location Info Plasma membrane, Cytosol;
Membrane Info Enzymes, Predicted intracellular proteins
Uniport_ID Q5VT25
HGNC ID HGNC:1737
OMIM ID 603412
Summary The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2018]
Target gene [CDC42BPA] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6007785 chr1 39 10 3 52 View
6011296 chr1 23 3 1 27 View
6013111 chr1 16 4 0 20 View
6015904 chr1 8 5 0 13 View

Target gene [CDC42BPA] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE19080 Expression array 38 Homo sapiens 3K Immunoarray2 HTLV-1 JH
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - CDC42BPA peak across samples

Peak Plot