Virus Dataset Detail

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Dataset Information
Accession GSE19080
Status 2010/2/14
Title Gene expression profiling in patients infected with HTLV-1: Identification of ATL and HAM/TSP-specific genetic profiles
Organism Homo sapiens
Experiment type Expression profiling by array
Summary We examined the gene expression profiles of CD4+ T-cells isolated from 7 ATL, 12 HAM/TSP and 11 AC (asymptomatic carriers) to identify gene signatures that may be characteristic for these particular diseases. Using gene expression arrays, we identified ~ 1039 immune-related genes that were differentially expressed in CD4+ T cells; using stringent exclusion criteria, a 122 gene signature could be divided into 3 groups: I) ATL-specific; II) common; and III) HAM/TSP-specific markers
Samples
GSM ID Sample info Characteristics Description
GSM472373 Asymtomatic Carrier, CD4+ T-cells from HTLV-1 infected patient (HISS0058) disease state:Asymtomatic Carrier (AC); source:Donor from Guyana; cell type:HTLV-1 Infected PBMC cells; gender:N/A; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472356 Adult T-cell leukemia, CD4+ T-cells from HTLV-1 infected patient (HISS0010) disease state:Adult T-cell leukemia (ATL); source:Donor from Antigua; cell type:HTLV-1 Infected PBMC cells; gender:Female; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472373 Asymtomatic Carrier, CD4+ T-cells from HTLV-1 infected patient (HISS0058) sample type:reference RNA n/a
GSM472356 Adult T-cell leukemia, CD4+ T-cells from HTLV-1 infected patient (HISS0010) sample type:reference RNA n/a
GSM472374 Healthy Donor, CD4+ T-cells from Healthy Donor (HISS0061) disease state:Healthy Donor; source:Donor from Martinique; cell type:No infected, control PBMC cells; gender:N/A; sample type:CD4+ T-Cells Isolated from Non Infected PBMC n/a
GSM472357 Adult T-cell leukemia, CD4+ T-cells from HTLV-1 infected patient (HISS0017) disease state:Adult T-cell leukemia (ATL); source:Donor from Martinique; cell type:HTLV-1 Infected PBMC cells; gender:N/A; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472374 Healthy Donor, CD4+ T-cells from Healthy Donor (HISS0061) sample type:reference RNA n/a
GSM472357 Adult T-cell leukemia, CD4+ T-cells from HTLV-1 infected patient (HISS0017) sample type:reference RNA n/a
GSM472358 Adult T-cell leukemia, CD4+ T-cells from HTLV-1 infected patient (HISS0018) disease state:Adult T-cell leukemia (ATL); source:Donor from Martinique; cell type:HTLV-1 Infected PBMC cells; gender:Female; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472358 Adult T-cell leukemia, CD4+ T-cells from HTLV-1 infected patient (HISS0018) sample type:reference RNA n/a
GSM472359 Adult T-cell leukemia, CD4+ T-cells from HTLV-1 infected patient (HISS0022) disease state:Adult T-cell leukemia (ATL); source:Donor from Antigua; cell type:HTLV-1 Infected PBMC cells; gender:Male; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472359 Adult T-cell leukemia, CD4+ T-cells from HTLV-1 infected patient (HISS0022) sample type:reference RNA n/a
GSM472360 Adult T-cell leukemia, CD4+ T-cells from HTLV-1 infected patient (HISS0023) disease state:Adult T-cell leukemia (ATL); source:Donor from Antigua; cell type:HTLV-1 Infected PBMC cells; gender:Male; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472360 Adult T-cell leukemia, CD4+ T-cells from HTLV-1 infected patient (HISS0023) sample type:reference RNA n/a
GSM472361 Adult T-cell leukemia, CD4+ T-cells from HTLV-1 infected patient (HISS0024) disease state:Adult T-cell leukemia (ATL); source:Donor from Antigua; cell type:HTLV-1 Infected PBMC cells; gender:Female; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472361 Adult T-cell leukemia, CD4+ T-cells from HTLV-1 infected patient (HISS0024) sample type:reference RNA n/a
GSM472362 Adult T-cell leukemia, CD4+ T-cells from HTLV-1 infected patient (HISS0029) disease state:Adult T-cell leukemia (ATL); source:Donor from Martinique; cell type:HTLV-1 Infected PBMC cells; gender:N/A; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472375 Healthy Donor, CD4+ T-cells from Healthy Donor (HISS0062) disease state:Healthy Donor; source:Donor from Martinique; cell type:No infected, control PBMC cells; gender:N/A; sample type:CD4+ T-Cells Isolated from Non Infected PBMC n/a
GSM472362 Adult T-cell leukemia, CD4+ T-cells from HTLV-1 infected patient (HISS0029) sample type:reference RNA n/a
GSM472375 Healthy Donor, CD4+ T-cells from Healthy Donor (HISS0062) sample type:reference RNA n/a
GSM472363 Asymtomatic Carrier, CD4+ T-cells from HTLV-1 infected patient (HISS0013) disease state:Asymtomatic Carrier (AC); source:Donor from Guyana; cell type:HTLV-1 Infected PBMC cells; gender:Female; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472376 Healthy Donor, CD4+ T-cells from Healthy Donor (HISS0063) disease state:Healthy Donor; source:Donor from Martinique; cell type:No infected, control PBMC cells; gender:N/A; sample type:CD4+ T-Cells Isolated from Non Infected PBMC n/a
GSM472363 Asymtomatic Carrier, CD4+ T-cells from HTLV-1 infected patient (HISS0013) sample type:reference RNA n/a
GSM472376 Healthy Donor, CD4+ T-cells from Healthy Donor (HISS0063) sample type:reference RNA n/a
GSM472364 Asymtomatic Carrier, CD4+ T-cells from HTLV-1 infected patient (HISS0014) disease state:Asymtomatic Carrier (AC); source:Donor from Guyana; cell type:HTLV-1 Infected PBMC cells; gender:Female; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472377 Healthy Donor, CD4+ T-cells from Healthy Donor (HISS0064) disease state:Healthy Donor; source:Donor from Martinique; cell type:No infected, control PBMC cells; gender:N/A; sample type:CD4+ T-Cells Isolated from Non Infected PBMC n/a
GSM472388 Neurological disorder tropical spastic paraparesis, CD4+ T-cells from HTLV-1 infected patient (HISS0049) disease state:Neurological disorder tropical spastic paraparesis (HAM/TSP); source:Donor from Martinique; cell type:HTLV-1 Infected PBMC cells; gender:Male; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472377 Healthy Donor, CD4+ T-cells from Healthy Donor (HISS0064) sample type:reference RNA n/a
GSM472364 Asymtomatic Carrier, CD4+ T-cells from HTLV-1 infected patient (HISS0014) sample type:reference RNA n/a
GSM472378 Healthy Donor, CD4+ T-cells from Healthy Donor (HISS0065) disease state:Healthy Donor; source:Donor from Martinique; cell type:No infected, control PBMC cells; gender:N/A; sample type:CD4+ T-Cells Isolated from Non Infected PBMC n/a
GSM472388 Neurological disorder tropical spastic paraparesis, CD4+ T-cells from HTLV-1 infected patient (HISS0049) sample type:reference RNA n/a
GSM472378 Healthy Donor, CD4+ T-cells from Healthy Donor (HISS0065) sample type:reference RNA n/a
GSM472365 Asymtomatic Carrier, CD4+ T-cells from HTLV-1 infected patient (HISS0015) disease state:Asymtomatic Carrier (AC); source:Donor from Guyana; cell type:HTLV-1 Infected PBMC cells; gender:Male; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472379 Healthy Donor, CD4+ T-cells from Healthy Donor (HISS0066) disease state:Healthy Donor; source:Donor from Martinique; cell type:No infected, control PBMC cells; gender:N/A; sample type:CD4+ T-Cells Isolated from Non Infected PBMC n/a
GSM472389 Neurological disorder tropical spastic paraparesis, CD4+ T-cells from HTLV-1 infected patient (HISS0051) disease state:Neurological disorder tropical spastic paraparesis (HAM/TSP); source:Donor from Guyana; cell type:HTLV-1 Infected PBMC cells; gender:N/A; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472389 Neurological disorder tropical spastic paraparesis, CD4+ T-cells from HTLV-1 infected patient (HISS0051) sample type:reference RNA n/a
GSM472365 Asymtomatic Carrier, CD4+ T-cells from HTLV-1 infected patient (HISS0015) sample type:reference RNA n/a
GSM472379 Healthy Donor, CD4+ T-cells from Healthy Donor (HISS0066) sample type:reference RNA n/a
GSM472390 Neurological disorder tropical spastic paraparesis, CD4+ T-cells from HTLV-1 infected patient (HISS0052) disease state:Neurological disorder tropical spastic paraparesis (HAM/TSP); source:Donor from Guyana; cell type:HTLV-1 Infected PBMC cells; gender:N/A; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472390 Neurological disorder tropical spastic paraparesis, CD4+ T-cells from HTLV-1 infected patient (HISS0052) sample type:reference RNA n/a
GSM472366 Asymtomatic Carrier, CD4+ T-cells from HTLV-1 infected patient (HISS0042) disease state:Asymtomatic Carrier (AC); source:Donor from Martinique; cell type:HTLV-1 Infected PBMC cells; gender:Male; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472391 Neurological disorder tropical spastic paraparesis, CD4+ T-cells from HTLV-1 infected patient (HISS0053) disease state:Neurological disorder tropical spastic paraparesis (HAM/TSP); source:Donor from Guyana; cell type:HTLV-1 Infected PBMC cells; gender:N/A; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472380 Healthy Donor, CD4+ T-cells from Healthy Donor (HISS0067) disease state:Healthy Donor; source:Donor from Martinique; cell type:No infected, control PBMC cells; gender:N/A; sample type:CD4+ T-Cells Isolated from Non Infected PBMC n/a
GSM472366 Asymtomatic Carrier, CD4+ T-cells from HTLV-1 infected patient (HISS0042) sample type:reference RNA n/a
GSM472380 Healthy Donor, CD4+ T-cells from Healthy Donor (HISS0067) sample type:reference RNA n/a
GSM472391 Neurological disorder tropical spastic paraparesis, CD4+ T-cells from HTLV-1 infected patient (HISS0053) sample type:reference RNA n/a
GSM472381 Healthy Donor , CD4+ T-cells from Healthy Donor (HISS0060) disease state:Healthy Donor; source:Donor from Martinique; cell type:No infected, control PBMC cells; gender:N/A; sample type:CD4+ T-Cells Isolated from Non Infected PBMC n/a
GSM472367 Asymtomatic Carrier, CD4+ T-cells from HTLV-1 infected patient (HISS0044) disease state:Asymtomatic Carrier (AC); source:Donor from Martinique; cell type:HTLV-1 Infected PBMC cells; gender:Female; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472381 Healthy Donor , CD4+ T-cells from Healthy Donor (HISS0060) sample type:reference RNA n/a
GSM472392 Neurological disorder tropical spastic paraparesis, CD4+ T-cells from HTLV-1 infected patient (HISS0054) disease state:Neurological disorder tropical spastic paraparesis (HAM/TSP); source:Donor from Guyana; cell type:HTLV-1 Infected PBMC cells; gender:N/A; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472382 Neurological disorder tropical spastic paraparesis, CD4+ T-cells from HTLV-1 infected patient (HISS0021) disease state:Neurological disorder tropical spastic paraparesis (HAM/TSP); source:Donor from Martinique; cell type:HTLV-1 Infected PBMC cells; gender:Female; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472392 Neurological disorder tropical spastic paraparesis, CD4+ T-cells from HTLV-1 infected patient (HISS0054) sample type:reference RNA n/a
GSM472382 Neurological disorder tropical spastic paraparesis, CD4+ T-cells from HTLV-1 infected patient (HISS0021) sample type:reference RNA n/a
GSM472367 Asymtomatic Carrier, CD4+ T-cells from HTLV-1 infected patient (HISS0044) sample type:reference RNA n/a
GSM472383 Neurological disorder tropical spastic paraparesis, CD4+ T-cells from HTLV-1 infected patient (HISS0031) disease state:Neurological disorder tropical spastic paraparesis (HAM/TSP); source:Donor from Martinique; cell type:HTLV-1 Infected PBMC cells; gender:N/A; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472393 Neurological disorder tropical spastic paraparesis, CD4+ T-cells from HTLV-1 infected patient (HISS0055) disease state:Neurological disorder tropical spastic paraparesis (HAM/TSP); source:Donor from Guyana; cell type:HTLV-1 Infected PBMC cells; gender:N/A; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472383 Neurological disorder tropical spastic paraparesis, CD4+ T-cells from HTLV-1 infected patient (HISS0031) sample type:reference RNA n/a
GSM472368 Asymtomatic Carrier, CD4+ T-cells from HTLV-1 infected patient (HISS0045) disease state:Asymtomatic Carrier (AC); source:Donor from Martinique; cell type:HTLV-1 Infected PBMC cells; gender:Female; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472384 Neurological disorder tropical spastic paraparesis, CD4+ T-cells from HTLV-1 infected patient (HISS0040) disease state:Neurological disorder tropical spastic paraparesis (HAM/TSP); source:Donor from Martinique; cell type:HTLV-1 Infected PBMC cells; gender:Male; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472393 Neurological disorder tropical spastic paraparesis, CD4+ T-cells from HTLV-1 infected patient (HISS0055) sample type:reference RNA n/a
GSM472384 Neurological disorder tropical spastic paraparesis, CD4+ T-cells from HTLV-1 infected patient (HISS0040) sample type:reference RNA n/a
GSM472368 Asymtomatic Carrier, CD4+ T-cells from HTLV-1 infected patient (HISS0045) sample type:reference RNA n/a
GSM472385 Neurological disorder tropical spastic paraparesis, CD4+ T-cells from HTLV-1 infected patient (HISS0041) disease state:Neurological disorder tropical spastic paraparesis (HAM/TSP); source:Donor from Martinique; cell type:HTLV-1 Infected PBMC cells; gender:Male; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472369 Asymtomatic Carrier, CD4+ T-cells from HTLV-1 infected patient (HISS0046) disease state:Asymtomatic Carrier (AC); source:Donor from Martinique; cell type:HTLV-1 Infected PBMC cells; gender:Female; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472385 Neurological disorder tropical spastic paraparesis, CD4+ T-cells from HTLV-1 infected patient (HISS0041) sample type:reference RNA n/a
GSM472369 Asymtomatic Carrier, CD4+ T-cells from HTLV-1 infected patient (HISS0046) sample type:reference RNA n/a
GSM472386 Neurological disorder tropical spastic paraparesis, CD4+ T-cells from HTLV-1 infected patient (HISS0043) disease state:Neurological disorder tropical spastic paraparesis (HAM/TSP); source:Donor from Martinique; cell type:HTLV-1 Infected PBMC cells; gender:Male; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472370 Asymtomatic Carrier, CD4+ T-cells from HTLV-1 infected patient (HISS0047) disease state:Asymtomatic Carrier (AC); source:Donor from Martinique; cell type:HTLV-1 Infected PBMC cells; gender:Male; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472386 Neurological disorder tropical spastic paraparesis, CD4+ T-cells from HTLV-1 infected patient (HISS0043) sample type:reference RNA n/a
GSM472370 Asymtomatic Carrier, CD4+ T-cells from HTLV-1 infected patient (HISS0047) sample type:reference RNA n/a
GSM472371 Asymtomatic Carrier, CD4+ T-cells from HTLV-1 infected patient (HISS0056) disease state:Asymtomatic Carrier (AC); source:Donor from Guyana; cell type:HTLV-1 Infected PBMC cells; gender:N/A; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472371 Asymtomatic Carrier, CD4+ T-cells from HTLV-1 infected patient (HISS0056) sample type:reference RNA n/a
GSM472387 Neurological disorder tropical spastic paraparesis, CD4+ T-cells from HTLV-1 infected patient (HISS0048) disease state:Neurological disorder tropical spastic paraparesis (HAM/TSP); source:Donor from Martinique; cell type:HTLV-1 Infected PBMC cells; gender:Male; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472372 Asymtomatic Carrier, CD4+ T-cells from HTLV-1 infected patient (HISS0057) disease state:Asymtomatic Carrier (AC); source:Donor from Guyana; cell type:HTLV-1 Infected PBMC cells; gender:N/A; sample type:CD4+ T-Cells Isolated from HTLV-1 infected PBMC n/a
GSM472387 Neurological disorder tropical spastic paraparesis, CD4+ T-cells from HTLV-1 infected patient (HISS0048) sample type:reference RNA n/a
GSM472372 Asymtomatic Carrier, CD4+ T-cells from HTLV-1 infected patient (HISS0057) sample type:reference RNA n/a
Platform GPL9686  : Homo sapiens 3K Immunoarray2 HTLV-1 JH
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