HTLV1 Target gene Detail Information

> CDH4 Gene Search Result


Gene Information
Gene Name CDH4
Gene ID 1002
Gene Full Name cadherin 4
Gene Alias CAD4|R-CAD|RCAD
Transcripts ENSG00000179242
Virus HTLV1
Gene Type protein-coding
HPA Location Info Plasma membrane;
Membrane Info Predicted membrane proteins
Uniport_ID P55283
HGNC ID HGNC:1763
OMIM ID 603006
Summary This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Target gene [CDH4] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6000518 chr20 57 913 374 1344 View
6003155 chr20 20 51 108 179 View
6007146 chr20 45 13 1 59 View
6007542 chr20 20 5 29 54 View
6008157 chr20 44 3 0 47 View
6012608 chr20 5 5 12 22 View
6013137 chr20 11 4 5 20 View
6013579 chr20 12 6 1 19 View
6014863 chr20 15 0 0 15 View
6015011 chr20 14 1 0 15 View
6015857 chr20 13 0 0 13 View
6019505 chr20 5 3 0 8 View
6021160 chr20 4 0 2 6 View
6022585 chr20 5 0 0 5 View
6023578 chr20 2 0 2 4 View

Target gene [CDH4] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE19080 Expression array 38 Homo sapiens 3K Immunoarray2 HTLV-1 JH
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - CDH4 peak across samples

Peak Plot