Gene Information
|
Gene Name
|
CDK9 |
|
Gene ID
|
1025
|
|
Gene Full Name
|
cyclin dependent kinase 9 |
|
Gene Alias
|
C-2k|CDC2L4|CTK1|PITALRE|TAK |
|
Transcripts
|
ENSG00000136807
|
|
Virus
|
IV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm;Cytoplasmic bodies; 
|
|
Membrane Info
|
Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins |
|
Uniport_ID
|
P50750
|
|
HGNC ID
|
HGNC:1780
|
|
OMIM ID
|
603251 |
|
Summary
|
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008] |
Target gene [CDK9] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
| ID |
PMID |
Mutation |
Gene/Protein/Region |
Encoding Gene/Protein |
Disease |
Description |
Detail |
| 1 |
39565117 |
H274Y |
|
|
Cell line
|
D
G
T
|
View |
Target gene [CDK9] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE243629
|
scRNA-seq |
11 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE225706
|
Chip-seq |
6 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE135069
|
RNA-seq |
10 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE113702
|
Chip-seq |
52 |
Illumina NextSeq 500 (Homo sapiens);Illumina HiSeq 4000 (Homo sapiens) |
|
C GSE225704
|
ATAC-seq |
3 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
E C GSE156060
|
Chip-seq;RNA-seq |
28 |
Illumina NovaSeq 6000 (Homo sapiens) |
When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.
> Dataset: GSE156060 - CDK9 expression across samples
|
Volcano Plot
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Bar Plot
|
|
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IV Target gene Detail Information
