HTLV1 Target gene Detail Information

> CRADD Gene Search Result


Gene Information
Gene Name CRADD
Gene ID 8738
Gene Full Name CASP2 and RIPK1 domain containing adaptor with death domain
Gene Alias MRT34|RAIDD
Transcripts ENSG00000169372
Virus HTLV1
Gene Type protein-coding
HPA Location Info Cytosol;Nucleoplasm;
Membrane Info Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins
Uniport_ID P78560
HGNC ID HGNC:2340
OMIM ID 603454
Summary This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Target gene [CRADD] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6005068 chr12 91 6 0 97 View
6011051 chr12 22 5 1 28 View
6018811 chr12 6 2 0 8 View
6022596 chr12 0 5 0 5 View

Target gene [CRADD] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE19080 Expression array 38 Homo sapiens 3K Immunoarray2 HTLV-1 JH
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - CRADD peak across samples

Peak Plot