Gene Information
|
Gene Name
|
DICER1 |
|
Gene ID
|
23405
|
|
Gene Full Name
|
dicer 1, ribonuclease III |
|
Gene Alias
|
DCR1|Dicer|Dicer1e|GLOW|HERNA|K12H4.8-LIKE|MNG1|RMSE2|aviD |
|
Transcripts
|
ENSG00000100697
|
|
Virus
|
MCV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Cytosol; 
|
|
Membrane Info
|
Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins |
|
Uniport_ID
|
Q9UPY3
|
|
HGNC ID
|
HGNC:17098
|
|
OMIM ID
|
606241 |
|
Summary
|
This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. This protein also acts as a strong antiviral agent with activity against RNA viruses, including the Zika and SARS-CoV-2 viruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2021] |
Target gene [DICER1] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
Target gene [DICER1] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE147406
|
Chip-seq |
39 |
Illumina NextSeq 500 (Homo sapiens) |
|
C GSE124856
|
Chip-seq |
8 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE136867
|
scRNA-seq |
2 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE226438
|
scRNA-seq |
11 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE69877
|
Chip-seq |
10 |
Illumina HiSeq 2000 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens) |
|
C GSE230758
|
Chip-seq |
20 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE118056
|
scRNA-seq |
4 |
Illumina NovaSeq 6000 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE147406 - DICER1 peak across samples
|
Peak Plot
|
> Dataset: GSE124856 - DICER1 peak across samples
|
Peak Plot
|
> Dataset: GSE69877 - DICER1 peak across samples
|
Peak Plot
|
> Dataset: GSE230758 - DICER1 peak across samples
|
Peak Plot
|
|
|
MCV Target gene Detail Information
