Gene Information
|
Gene Name
|
DLC1 |
|
Gene ID
|
10395
|
|
Gene Full Name
|
DLC1 Rho GTPase activating protein |
|
Gene Alias
|
ARHGAP7|HP|STARD12|p122-RhoGAP |
|
Transcripts
|
ENSG00000164741
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Cytosol;Endoplasmic reticulum, Vesicles; 
|
|
Membrane Info
|
Cancer-related genes, Plasma proteins, Predicted intracellular proteins |
|
Uniport_ID
|
Q96QB1
|
|
HGNC ID
|
HGNC:2897
|
|
OMIM ID
|
604258 |
|
Summary
|
This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.[provided by RefSeq, Apr 2010] |
Target gene [DLC1] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6008868 |
chr8 |
37 |
3 |
1 |
41 |
View |
| 6009973 |
chr8 |
5 |
2 |
27 |
34 |
View |
| 6010591 |
chr8 |
4 |
26 |
0 |
30 |
View |
| 6012330 |
chr8 |
17 |
4 |
2 |
23 |
View |
Target gene [DLC1] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE19080
|
Expression array |
38 |
Homo sapiens 3K Immunoarray2 HTLV-1 JH |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - DLC1 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
