Gene Information
|
Gene Name
|
DPYSL2 |
|
Gene ID
|
1808
|
|
Gene Full Name
|
dihydropyrimidinase like 2 |
|
Gene Alias
|
CRMP-2|CRMP2|DHPRP2|DRP-2|DRP2|N2A3|ULIP-2|ULIP2 |
|
Transcripts
|
ENSG00000092964
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Plasma membrane, Microtubules, Cytosol;Mitotic spindle, Primary cilium;
|
|
Membrane Info
|
Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
|
Uniport_ID
|
Q16555
|
|
HGNC ID
|
HGNC:3014
|
|
OMIM ID
|
602463 |
|
Summary
|
This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011] |
Target gene [DPYSL2] related to VISs
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6004097 |
chr8 |
31 |
21 |
77 |
129 |
View |
| 6006775 |
chr8 |
62 |
1 |
0 |
63 |
View |
| 6014163 |
chr8 |
9 |
2 |
6 |
17 |
View |
| 6016057 |
chr8 |
12 |
1 |
0 |
13 |
View |
| 6024998 |
chr8 |
0 |
3 |
0 |
3 |
View |
| 6032756 |
chr8 |
0 |
0 |
0 |
0 |
View |
Target gene [DPYSL2] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE19080
|
Expression array |
38 |
Homo sapiens 3K Immunoarray2 HTLV-1 JH |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - DPYSL2 peak across samples
|
Peak Plot
|
|
|