MCV Target gene Detail Information

> EIF4EBP2 Gene Search Result


Gene Information
Gene Name EIF4EBP2
Gene ID 1979
Gene Full Name eukaryotic translation initiation factor 4E binding protein 2
Gene Alias 4EBP2|PHASII
Transcripts ENSG00000148730
Virus MCV
Gene Type protein-coding
HPA Location Info Nucleoplasm, Mitochondria;
Membrane Info Predicted intracellular proteins
Uniport_ID Q13542
HGNC ID HGNC:3289
OMIM ID 602224
Summary This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. [provided by RefSeq, Oct 2008]
Target gene [EIF4EBP2] related to virus gene/protein/region

Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section


ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 21841310 R7A
Small T
MCPyV_gp4
Carcinoma, merkel cell
Cell line
L
T
View
2 21841310 L142A
Small T
MCPyV_gp4
Carcinoma, merkel cell
Cell line
L
T
View
3 21841310 D44N
Small T
MCPyV_gp4
Carcinoma, merkel cell
Cell line
L
T
View

Target gene [EIF4EBP2] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE147406
Chip-seq 39 Illumina NextSeq 500 (Homo sapiens)
C
  GSE124856
Chip-seq 8 Illumina NextSeq 500 (Homo sapiens)
GSE226438 scRNA-seq 11 Illumina NovaSeq 6000 (Homo sapiens)
GSE117988 scRNA-seq 6 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE69877
Chip-seq 10 Illumina HiSeq 2000 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
C
  GSE230758
Chip-seq 20 Illumina HiSeq 2500 (Homo sapiens)
GSE118056 scRNA-seq 4 Illumina NovaSeq 6000 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE147406 - EIF4EBP2 peak across samples

Peak Plot


> Dataset: GSE124856 - EIF4EBP2 peak across samples

Peak Plot


> Dataset: GSE69877 - EIF4EBP2 peak across samples

Peak Plot


> Dataset: GSE230758 - EIF4EBP2 peak across samples

Peak Plot