Gene Information
|
Gene Name
|
FUT8 |
|
Gene ID
|
2530
|
|
Gene Full Name
|
fucosyltransferase 8 |
|
Gene Alias
|
CDGF|CDGF1 |
|
Transcripts
|
ENSG00000033170
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Golgi apparatus;Nucleoplasm, Cytosol;
|
|
Membrane Info
|
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins |
|
Uniport_ID
|
Q9BYC5
|
|
HGNC ID
|
HGNC:4019
|
|
OMIM ID
|
602589 |
|
Summary
|
This gene encodes an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011] |
Target gene [FUT8] related to VISs
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6000782 |
chr14 |
818 |
40 |
3 |
861 |
View |
| 6003153 |
chr14 |
134 |
44 |
1 |
179 |
View |
| 6017246 |
chr14 |
8 |
3 |
0 |
11 |
View |
| 6017247 |
chr14 |
8 |
3 |
0 |
11 |
View |
| 6017248 |
chr14 |
8 |
3 |
0 |
11 |
View |
| 6019318 |
chr14 |
3 |
5 |
0 |
8 |
View |
| 6020962 |
chr14 |
6 |
0 |
0 |
6 |
View |
Target gene [FUT8] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE19080
|
Expression array |
38 |
Homo sapiens 3K Immunoarray2 HTLV-1 JH |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - FUT8 peak across samples
|
Peak Plot
|
|
|