Gene Information
|
Gene Name
|
GBE1 |
|
Gene ID
|
2632
|
|
Gene Full Name
|
1,4-alpha-glucan branching enzyme 1 |
|
Gene Alias
|
APBD|GBE|GSD4 |
|
Transcripts
|
ENSG00000114480
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Cytosol; 
|
|
Membrane Info
|
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins |
|
Uniport_ID
|
Q04446
|
|
HGNC ID
|
HGNC:4180
|
|
OMIM ID
|
607839 |
|
Summary
|
The protein encoded by this gene is a glycogen branching enzyme that catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on the same or a neighboring glycogen chain. Branching of the chains is essential to increase the solubility of the glycogen molecule and, consequently, in reducing the osmotic pressure within cells. Highest level of this enzyme are found in liver and muscle. Mutations in this gene are associated with glycogen storage disease IV (also known as Andersen's disease). [provided by RefSeq, Jul 2008] |
Target gene [GBE1] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6006202 |
chr3 |
1 |
2 |
70 |
73 |
View |
| 6018077 |
chr3 |
2 |
7 |
0 |
9 |
View |
| 6018383 |
chr3 |
9 |
0 |
0 |
9 |
View |
| 6021940 |
chr3 |
3 |
0 |
2 |
5 |
View |
| 6023402 |
chr3 |
3 |
1 |
0 |
4 |
View |
| 6028971 |
chr3 |
1 |
0 |
0 |
1 |
View |
| 6030268 |
chr3 |
1 |
0 |
0 |
1 |
View |
| 6032178 |
chr3 |
0 |
0 |
0 |
0 |
View |
Target gene [GBE1] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE19080
|
Expression array |
38 |
Homo sapiens 3K Immunoarray2 HTLV-1 JH |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - GBE1 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
