HTLV1 Target gene Detail Information

> GFRA1 Gene Search Result


Gene Information
Gene Name GFRA1
Gene ID 2674
Gene Full Name GDNF family receptor alpha 1
Gene Alias GDNFR|GDNFR-alpha-1|GDNFRA|GFR-ALPHA-1|GFRalpha-1|RET1L|RETL1|RHDA4|TRNR1
Transcripts ENSG00000151892
Virus HTLV1
Gene Type protein-coding
HPA Location Info Golgi apparatus;Nucleoplasm;
Membrane Info Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID P56159
HGNC ID HGNC:4243
OMIM ID 601496
Summary This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
Target gene [GFRA1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6019294 chr10 6 1 1 8 View
6021018 chr10 4 2 0 6 View
6024851 chr10 2 1 0 3 View

Target gene [GFRA1] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE19080 Expression array 38 Homo sapiens 3K Immunoarray2 HTLV-1 JH
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - GFRA1 peak across samples

Peak Plot