Gene Information
|
Gene Name
|
GSK3B |
|
Gene ID
|
2932
|
|
Gene Full Name
|
glycogen synthase kinase 3 beta |
|
Gene Alias
|
- |
|
Transcripts
|
ENSG00000082701
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm;Vesicles, Cytosol; 
|
|
Membrane Info
|
Enzymes, Predicted intracellular proteins, Predicted membrane proteins |
|
Uniport_ID
|
P49841
|
|
HGNC ID
|
HGNC:4617
|
|
OMIM ID
|
605004 |
|
Summary
|
The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. [provided by RefSeq, Aug 2017] |
Target gene [GSK3B] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6016755 |
chr3 |
2 |
10 |
0 |
12 |
View |
| 6022486 |
chr3 |
4 |
1 |
0 |
5 |
View |
| 6025271 |
chr3 |
2 |
1 |
0 |
3 |
View |
| 6025863 |
chr3 |
0 |
2 |
0 |
2 |
View |
| 6030203 |
chr3 |
1 |
0 |
0 |
1 |
View |
Target gene [GSK3B] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE19080
|
Expression array |
38 |
Homo sapiens 3K Immunoarray2 HTLV-1 JH |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - GSK3B peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
