HBV Target gene Detail Information

> GSTA1 Gene Search Result


Gene Information
Gene Name GSTA1
Gene ID 2938
Gene Full Name glutathione S-transferase alpha 1
Gene Alias GST-epsilon|GST2|GSTA1-1|GTH1
Transcripts ENSG00000243955
Virus HBV
Gene Type protein-coding
HPA Location Info Cytosol;
Membrane Info Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins
Uniport_ID P08263
HGNC ID HGNC:4626
OMIM ID 138359
Summary This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. This action is an important step in detoxification of these compounds. This subfamily of enzymes has a particular role in protecting cells from reactive oxygen species and the products of peroxidation. Polymorphisms in this gene influence the ability of individuals to metabolize different drugs. This gene is located in a cluster of similar genes and pseudogenes on chromosome 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Target gene [GSTA1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004882 chr6 67 0 0 67 View
1040498 chr6 0 10 0 10 View
1040499 chr6 0 10 0 10 View
1040500 chr6 6 8 0 14 View
1040501 chr6 6 8 0 14 View
1040502 chr6 6 7 0 13 View
1040503 chr6 6 7 0 13 View
1040504 chr6 6 7 0 13 View
1040505 chr6 6 7 0 13 View
1040506 chr6 6 7 0 13 View
1040507 chr6 6 7 0 13 View

Target gene [GSTA1] related to Omics data
Data ID Experiment type Sample number Platform
S
  GSE252863 		scRNA-seq 10 Illumina HiSeq 2500 (Homo sapiens)
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
C
  GSE35465 		Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
S
  GSE199850 		scRNA-seq 1 HiSeq X Ten (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
S
  GSE247322 		scRNA-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130 		Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
E
  GSE100400 		Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
E
  GSE94660 		RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE100400 - GSTA1 expression across samples

Volcano Plot

Bar Plot

> Dataset: GSE94660 - GSTA1 expression across samples

Volcano Plot

Bar Plot