Gene Information
|
Gene Name
|
IFNAR1 |
|
Gene ID
|
3454
|
|
Gene Full Name
|
interferon alpha and beta receptor subunit 1 |
|
Gene Alias
|
AVP|IFN-alpha-REC|IFNAR|IFNBR|IFRC|IMD106 |
|
Transcripts
|
ENSG00000142166
|
|
Virus
|
MCV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
|
|
Membrane Info
|
Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
|
Uniport_ID
|
P17181
|
|
HGNC ID
|
HGNC:5432
|
|
OMIM ID
|
107450 |
|
Summary
|
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor. [provided by RefSeq, Jul 2020] |
Target gene [IFNAR1] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
| ID |
PMID |
Mutation |
Gene/Protein/Region |
Encoding Gene/Protein |
Disease |
Description |
Detail |
| 1 |
39110744 |
R102A |
Small T
|
MCPyV_gp4
|
Cell line
|
I
T
|
View |
Target gene [IFNAR1] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE147406
|
Chip-seq |
39 |
Illumina NextSeq 500 (Homo sapiens) |
|
C GSE124856
|
Chip-seq |
8 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE226438
|
scRNA-seq |
11 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE117988
|
scRNA-seq |
6 |
Illumina HiSeq 2500 (Homo sapiens) |
|
C GSE69877
|
Chip-seq |
10 |
Illumina HiSeq 2000 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens) |
|
C GSE230758
|
Chip-seq |
20 |
Illumina HiSeq 2500 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE147406 - IFNAR1 peak across samples
|
Peak Plot
|
> Dataset: GSE124856 - IFNAR1 peak across samples
|
Peak Plot
|
> Dataset: GSE69877 - IFNAR1 peak across samples
|
Peak Plot
|
> Dataset: GSE230758 - IFNAR1 peak across samples
|
Peak Plot
|
|
|
MCV Target gene Detail Information
