Gene Name	IGF2R
Gene ID	3482
Gene Full Name	insulin like growth factor 2 receptor
Gene Alias	CD222|CI-M6PR|CIMPR|M6P-R|M6P/IGF2R|MPR 300|MPR1|MPR300|MPRI
Transcripts	ENSG00000197081
Virus	HBV
Gene Type	protein-coding
HPA Location Info	Golgi apparatus;Vesicles;
Membrane Info	Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	P11717
HGNC ID	HGNC:5467
OMIM ID	147280
Summary	This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003074	chr6	84	65	21	170	View
1003075	chr6	85	65	20	170	View
1003224	chr6	74	60	20	154	View
1003226	chr6	74	60	20	154	View
1003234	chr6	74	60	19	153	View
1003236	chr6	74	60	19	153	View
1003293	chr6	75	57	15	147	View
1003328	chr6	74	55	14	143	View
1003375	chr6	73	54	11	138	View
1003390	chr6	76	50	11	137	View
1003404	chr6	75	49	11	135	View
1014895	chr6	2	1	0	3	View
1021393	chr6	74	60	20	154	View
1022100	chr6	76	50	11	137	View
1022101	chr6	74	60	19	153	View
1022701	chr6	75	49	11	135	View
1022702	chr6	74	55	14	143	View
1022927	chr6	73	54	11	138	View

Data ID	Experiment type	Sample number	Platform
GSE252863	scRNA-seq	10	Illumina HiSeq 2500 (Homo sapiens)
GSE236281	RNA-seq	12	Illumina MiSeq (Homo sapiens)
C   GSE35465	Chip-seq;RNA-seq	6	Illumina HiSeq 2000 (Homo sapiens)
C   GSE68402	Chip-seq	26	Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
S   GSE247322	scRNA-seq	27	Illumina NovaSeq 6000 (Homo sapiens)
TCGA_LIHC_HBV	DNA methylation sequencing;RNA-seq	97	TCGA
C   GSE270130	Chip-seq	27	Illumina NovaSeq 6000 (Homo sapiens)
GSE224901	RNA-seq	21	Illumina NovaSeq 6000 (Homo sapiens)
C   GSE100400	Chip-seq;RNA-seq;4C_cccDNA	31	Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897	RNA-seq	95	Illumina HiSeq 4000 (Homo sapiens)
GSE262515	RNA-seq	21	Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345	RNA-seq	4	Illumina HiSeq 2500 (Homo sapiens)
C   GSE131257	ATAC-seq;RNA-seq	19	Illumina HiSeq 2500 (Homo sapiens)
GSE94660	RNA-seq	42	Illumina HiSeq 2500 (Homo sapiens)

• scRNA data
• Genome binding/occupancy profiling

When the query gene is differentially changed in the dataset, a feature/violin plot will be displayed.

> Dataset: GSE247322 - Gene expression in cell subsets