HTLV1 Target gene Detail Information

> IMPDH1 Gene Search Result


Gene Information
Gene Name IMPDH1
Gene ID 3614
Gene Full Name inosine monophosphate dehydrogenase 1
Gene Alias IMPD|IMPD1|IMPDH-I|LCA11|RP10|sWSS2608
Transcripts ENSG00000106348
Virus HTLV1
Gene Type protein-coding
HPA Location Info Cytosol;Rods & Rings;
Membrane Info Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins
Uniport_ID P20839
HGNC ID HGNC:6052
OMIM ID 146690
Summary The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Target gene [IMPDH1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6008565 chr7 41 3 0 44 View

Target gene [IMPDH1] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
E
  GSE19080 		Expression array 38 Homo sapiens 3K Immunoarray2 HTLV-1 JH
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE19080 - IMPDH1 expression across samples

Volcano Plot

Bar Plot