HTLV1 Target gene Detail Information

> IRF8 Gene Search Result


Gene Information
Gene Name IRF8
Gene ID 3394
Gene Full Name interferon regulatory factor 8
Gene Alias H-ICSBP|ICSBP|ICSBP1|IMD32A|IMD32B|IRF-8
Transcripts ENSG00000140968
Virus HTLV1
Gene Type protein-coding
HPA Location Info Nucleoplasm;
Membrane Info Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors
Uniport_ID Q02556
HGNC ID HGNC:5358
OMIM ID 601565
Summary Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. [provided by RefSeq, Jul 2008]
Target gene [IRF8] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6011620 chr16 24 2 0 26 View

Target gene [IRF8] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
E
  GSE19080 		Expression array 38 Homo sapiens 3K Immunoarray2 HTLV-1 JH
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE19080 - IRF8 expression across samples

Volcano Plot

Bar Plot