HTLV1 Target gene Detail Information

> ITGA2 Gene Search Result


Gene Information
Gene Name ITGA2
Gene ID 3673
Gene Full Name integrin subunit alpha 2
Gene Alias BR|CD49B|GPIa|HPA-5|VLA-2|VLAA2
Transcripts ENSG00000164171
Virus HTLV1
Gene Type protein-coding
HPA Location Info
Membrane Info Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted membrane proteins
Uniport_ID P17301
HGNC ID HGNC:6137
OMIM ID 192974
Summary This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Target gene [ITGA2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6003255 chr5 116 32 23 171 View
6013505 chr5 19 0 0 19 View
6021557 chr5 6 0 0 6 View

Target gene [ITGA2] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE19080 Expression array 38 Homo sapiens 3K Immunoarray2 HTLV-1 JH
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - ITGA2 peak across samples

Peak Plot