Gene Information
|
Gene Name
|
ITSN1 |
|
Gene ID
|
6453
|
|
Gene Full Name
|
intersectin 1 |
|
Gene Alias
|
ITSN|SH3D1A|SH3P17 |
|
Transcripts
|
ENSG00000205726
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Plasma membrane; 
|
|
Membrane Info
|
Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins |
|
Uniport_ID
|
Q15811
|
|
HGNC ID
|
HGNC:6183
|
|
OMIM ID
|
602442 |
|
Summary
|
The protein encoded by this gene is a cytoplasmic membrane-associated protein that indirectly coordinates endocytic membrane traffic with the actin assembly machinery. In addition, the encoded protein may regulate the formation of clathrin-coated vesicles and could be involved in synaptic vesicle recycling. This protein has been shown to interact with dynamin, CDC42, SNAP23, SNAP25, SPIN90, EPS15, EPN1, EPN2, and STN2. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been characterized so far. [provided by RefSeq, Jul 2008] |
Target gene [ITSN1] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6003082 |
chr21 |
47 |
115 |
22 |
184 |
View |
| 6005901 |
chr21 |
67 |
5 |
7 |
79 |
View |
| 6006114 |
chr21 |
52 |
22 |
0 |
74 |
View |
| 6013834 |
chr21 |
17 |
1 |
0 |
18 |
View |
| 6021773 |
chr21 |
5 |
0 |
0 |
5 |
View |
| 6022597 |
chr21 |
5 |
0 |
0 |
5 |
View |
| 6023187 |
chr21 |
1 |
3 |
0 |
4 |
View |
Target gene [ITSN1] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE19080
|
Expression array |
38 |
Homo sapiens 3K Immunoarray2 HTLV-1 JH |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - ITSN1 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
