Gene Information
|
Gene Name
|
MAF |
|
Gene ID
|
4094
|
|
Gene Full Name
|
MAF bZIP transcription factor |
|
Gene Alias
|
AYGRP|CCA4|CTRCT21|c-MAF |
|
Transcripts
|
ENSG00000178573
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm, Nuclear bodies;Golgi apparatus, Vesicles; 
|
|
Membrane Info
|
Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors |
|
Uniport_ID
|
O75444
|
|
HGNC ID
|
HGNC:6776
|
|
OMIM ID
|
177075 |
|
Summary
|
The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010] |
Target gene [MAF] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6004592 |
chr16 |
9 |
61 |
41 |
111 |
View |
| 6010520 |
chr16 |
16 |
13 |
1 |
30 |
View |
| 6010521 |
chr16 |
16 |
13 |
1 |
30 |
View |
| 6012575 |
chr16 |
14 |
8 |
0 |
22 |
View |
| 6020370 |
chr16 |
6 |
1 |
0 |
7 |
View |
Target gene [MAF] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
E GSE19080
|
Expression array |
38 |
Homo sapiens 3K Immunoarray2 HTLV-1 JH |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.
> Dataset: GSE19080 - MAF expression across samples
|
Volcano Plot
|
Bar Plot
|
|
|
HTLV1 Target gene Detail Information
