HTLV1 Target gene Detail Information

> MBNL2 Gene Search Result


Gene Information
Gene Name MBNL2
Gene ID 10150
Gene Full Name muscleblind like splicing regulator 2
Gene Alias MBLL|MBLL39|PRO2032
Transcripts ENSG00000139793
Virus HTLV1
Gene Type protein-coding
HPA Location Info Nucleoplasm;
Membrane Info Predicted intracellular proteins
Uniport_ID Q5VZF2
HGNC ID HGNC:16746
OMIM ID 607327
Summary This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. [provided by RefSeq, Mar 2012]
Target gene [MBNL2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6008525 chr13 29 13 2 44 View
6011436 chr13 15 11 0 26 View
6023682 chr13 2 2 0 4 View
6030450 chr13 0 0 0 0 View
6030585 chr13 0 0 0 0 View

Target gene [MBNL2] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE19080 Expression array 38 Homo sapiens 3K Immunoarray2 HTLV-1 JH
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - MBNL2 peak across samples

Peak Plot